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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 8 — Aug. 10, 2007

Optical density of the aging human ocular media in the visible and the UV

Jan van de Kraats and Dirk van Norren  »View Author Affiliations


JOSA A, Vol. 24, Issue 7, pp. 1842-1857 (2007)
http://dx.doi.org/10.1364/JOSAA.24.001842


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Abstract

We analyzed the literature on the absorption in the young and aging human eye media. Five templates were derived to provide an adequate description of the spectra from 300 to 700 nm for the lens, cornea, aqueous, and vitreous. Two templates were found in all media. They stand for Rayleigh scatter and the absorbance of tryptophan. Three additional templates for the lens represent absorbance in kynurenine derivatives, such as 3-hydroxykynurenine glucoside (3HKG), and absorbance in two substances found at older age. Except for Rayleigh scatter, all templates have a Gaussian shape. Aging-trend functions were derived that show a linear slope on an age-squared scale. The result can be used to correct for media losses in visual perception tasks, in fundus reflectometry, and in studies on light damage.

© 2007 Optical Society of America

OCIS Codes
(170.4470) Medical optics and biotechnology : Ophthalmology
(290.2200) Scattering : Extinction
(300.1030) Spectroscopy : Absorption
(330.3350) Vision, color, and visual optics : Vision - laser damage
(330.4060) Vision, color, and visual optics : Vision modeling
(330.5370) Vision, color, and visual optics : Physiological optics

ToC Category:
Vision and Color

History
Original Manuscript: November 1, 2006
Revised Manuscript: January 30, 2007
Manuscript Accepted: February 1, 2007
Published: June 13, 2007

Virtual Issues
Vol. 2, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Jan van de Kraats and Dirk van Norren, "Optical density of the aging human ocular media in the visible and the UV," J. Opt. Soc. Am. A 24, 1842-1857 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-24-7-1842


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