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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 4 — Apr. 1, 2009

Mass detection on mammograms: influence of signal shape uncertainty on human and model observers

C. Castella, M. P. Eckstein, C. K. Abbey, K. Kinkel, F. R. Verdun, R. S. Saunders, E. Samei, and F. O. Bochud  »View Author Affiliations


JOSA A, Vol. 26, Issue 2, pp. 425-436 (2009)
http://dx.doi.org/10.1364/JOSAA.26.000425


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Abstract

We studied the influence of signal variability on human and model observers for detection tasks with realistic simulated masses superimposed on real patient mammographic backgrounds and synthesized mammographic backgrounds (clustered lumpy backgrounds, CLB). Results under the signal-known-exactly (SKE) paradigm were compared with signal-known-statistically (SKS) tasks for which the observers did not have prior knowledge of the shape or size of the signal. Human observers' performance did not vary significantly when benign masses were superimposed on real images or on CLB. Uncertainty and variability in signal shape did not degrade human performance significantly compared with the SKE task, while variability in signal size did. Implementation of appropriate internal noise components allowed the fit of model observers to human performance.

© 2009 Optical Society of America

OCIS Codes
(170.3830) Medical optics and biotechnology : Mammography
(330.1880) Vision, color, and visual optics : Detection
(330.4060) Vision, color, and visual optics : Vision modeling
(330.5020) Vision, color, and visual optics : Perception psychology
(330.5510) Vision, color, and visual optics : Psychophysics

ToC Category:
Vision, Color, and Visual Optics

History
Original Manuscript: September 9, 2008
Revised Manuscript: December 11, 2008
Manuscript Accepted: December 14, 2008
Published: January 30, 2009

Virtual Issues
Vol. 4, Iss. 4 Virtual Journal for Biomedical Optics

Citation
C. Castella, M. P. Eckstein, C. K. Abbey, K. Kinkel, F. R. Verdun, R. S. Saunders, E. Samei, and F. O. Bochud, "Mass detection on mammograms: influence of signal shape uncertainty on human and model observers," J. Opt. Soc. Am. A 26, 425-436 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-26-2-425

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