Spectrally resolved three-dimensional bioluminescence tomography with a level-set strategy
JOSA A, Vol. 27, Issue 6, pp. 1413-1423 (2010)
http://dx.doi.org/10.1364/JOSAA.27.001413
Enhanced HTML 
Acrobat PDF (782 KB)
Abstract
A reconstruction method is presented for spectrally resolved three-dimensional bioluminescence tomography (BLT) in heterogeneous media using a level-set strategy. In order to reconstruct internal bioluminescent sources, a level-set strategy is utilized to quantitatively localize the distribution of bioluminescent sources. The results in numerical phantom experiments clearly show that the proposed method can tolerate different initial values and noise levels and, furthermore, can work credibly even when the number of phases (levels) is not known a priori. In addition, a mouse atlas reconstruction is employed to demonstrate the effectiveness of the proposed method in turbid mouse geometry. Finally, the physical experiment further evaluates the method’s potential in practical applications.
© 2010 Optical Society of America
OCIS Codes
(100.3190) Image processing : Inverse problems
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
(170.6960) Medical optics and biotechnology : Tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: August 20, 2009
Revised Manuscript: March 15, 2010
Manuscript Accepted: April 6, 2010
Published: May 21, 2010
Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics
Citation
Kai Liu, Xin Yang, Dan Liu, Chenghu Qin, Junting Liu, Zhijun Chang, Min Xu, and Jie Tian, "Spectrally resolved three-dimensional bioluminescence tomography with a level-set strategy," J. Opt. Soc. Am. A 27, 1413-1423 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-27-6-1413
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Semi-Three-Dimensional Algorithm for Time-Resolved Diffuse Optical Tomography by Use of the Generalized Pulse Spectrum Technique (AO)
- Fluorescence tomography with simulated data based on the equation of radiative transfer (OL)
- Diffuse optical tomography with spectral constraints and wavelength optimization (AO)
- A fast bioluminescent source localization method based on generalized graph cuts with mouse model validations (OE)
- Evaluation of the simplified spherical harmonics approximation in bioluminescence tomography through heterogeneous mouse models (OE)
Related Conference Papers
- Experimental validation of the influence of fiberoptic probe design on the origin of detected fluorescence
- The Kirchhoff Approximation in diffuse optical tomography
- Three-Dimensional Fluorescent Tomography in the Presence of Heterogeneous Absorption Background.
- Kinetic fluorescence optical diffusion tomography
- Simulation of Oblique-Incidence Probe Geometries for Depth-Resolved Fluorescence Spectroscopy
« Previous Article | Next Article »
OSA is a member of 