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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 7 — Jun. 25, 2012

Model-resolution based regularization improves near infrared diffuse optical tomography

Sree Harsha Katamreddy and Phaneendra K. Yalavarthy  »View Author Affiliations


JOSA A, Vol. 29, Issue 5, pp. 649-656 (2012)
http://dx.doi.org/10.1364/JOSAA.29.000649


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Abstract

Diffuse optical tomographic imaging is known to be an ill-posed problem, and a penalty/regularization term is used in image reconstruction (inverse problem) to overcome this limitation. Two schemes that are prevalent are spatially varying (exponential) and constant (standard) regularizations/penalties. A scheme that is also spatially varying but uses the model information is introduced based on the model-resolution matrix. This scheme, along with exponential and standard regularization schemes, is evaluated objectively based on model-resolution and data-resolution matrices. This objective analysis showed that resolution characteristics are better for spatially varying penalties compared to standard regularization; and among spatially varying regularization schemes, the model-resolution based regularization fares well in providing improved data-resolution and model-resolution characteristics. The verification of the same is achieved by performing numerical experiments in reconstructing 1% noisy data involving simple two- and three-dimensional imaging domains.

© 2012 Optical Society of America

OCIS Codes
(100.3190) Image processing : Inverse problems
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 16, 2011
Manuscript Accepted: January 17, 2012
Published: April 4, 2012

Virtual Issues
Vol. 7, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Sree Harsha Katamreddy and Phaneendra K. Yalavarthy, "Model-resolution based regularization improves near infrared diffuse optical tomography," J. Opt. Soc. Am. A 29, 649-656 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-29-5-649

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