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Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors |
JOSA A, Vol. 29, Issue 7, pp. 1367-1376 (2012)
http://dx.doi.org/10.1364/JOSAA.29.001367
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Abstract
We have analyzed the effectiveness of field-matter integral overlap between target index distribution and local near-fields to assess detection sensitivity of surface plasmon resonance (SPR) biosensors. The correlation of the overlap with sensitivity was clear. An overlap integral defined with lateral electric field intensity produced the highest correlation due to tangential continuity across a boundary. Among the three detection scenarios considered, the correlation for localized SPR sensing was slightly lower than that of thin film-based detection and improved with an increased fill factor in the structure. The results will be useful to maximize the optical signature created by target interactions and to produce highest sensitivity of SPR detection to variations when target or field distribution is not uniform.
© 2012 Optical Society of America
OCIS Codes
(240.6680) Optics at surfaces : Surface plasmons
(280.4788) Remote sensing and sensors : Optical sensing and sensors
(250.5403) Optoelectronics : Plasmonics
(310.6628) Thin films : Subwavelength structures, nanostructures
ToC Category:
Optics at Surfaces
History
Original Manuscript: January 3, 2012
Revised Manuscript: March 5, 2012
Manuscript Accepted: April 12, 2012
Published: June 21, 2012
Virtual Issues
Vol. 7, Iss. 9 Virtual Journal for Biomedical Optics
Citation
Wonju Lee and Donghyun Kim, "Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors," J. Opt. Soc. Am. A 29, 1367-1376 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-29-7-1367
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