OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 6 — Jun. 13, 2006

Speckle reduction in OCT using massively-parallel detection and frequency-domain ranging

A. E. Desjardins, B. J. Vakoc, G. J. Tearney, and B. E. Bouma  »View Author Affiliations


Optics Express, Vol. 14, Issue 11, pp. 4736-4745 (2006)
http://dx.doi.org/10.1364/OE.14.004736


View Full Text Article

Enhanced HTML    Acrobat PDF (358 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Speckle noise significantly limits the information content provided by coherent optical imaging methods such as optical coherence tomography and its recent derivative, optical frequency-domain imaging (OFDI). In this paper, we demonstrate a novel OFDI system that simultaneously acquires hundreds of angularly resolved images, which can be compounded to reduce speckle noise. The system comprises an InGaAs line-scan camera and an interferometer, configured so that the elements of the detector array simultaneously capture light spanning a backscattering angular range of 32 degrees. On successive read-outs of the array, the wavelength of the laser source was stepped through a range of 130 nm centered at 1295 nm to concurrently generate 400 angle-resolved OFDI images. A theory of angle-resolved OFDI and the design equations of the system are presented. Incoherent averaging of the angle-resolved data is shown to yield substantial speckle reduction (as high as an 8 dB SNR improvement) in images of a tissue phantom and esophageal tissue ex vivo.

© 2006 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 2, 2006
Revised Manuscript: May 9, 2006
Manuscript Accepted: May 15, 2006
Published: May 29, 2006

Virtual Issues
Vol. 1, Iss. 6 Virtual Journal for Biomedical Optics

Citation
A. E. Desjardins, B. J. Vakoc, G. J. Tearney, and B. E. Bouma, "Speckle Reduction in OCT using Massively-Parallel Detection and Frequency-Domain Ranging," Opt. Express 14, 4736-4745 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-14-11-4736


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003). [CrossRef] [PubMed]
  2. R. Huber, M. Wojtkowski, J. G. Fujimoto, J. Y. Jiang, and A. E. Cable, "Three-dimensional and C-mode OCT imaging with a compact, frequency swept laser source at 1300 nm," Opt. Express 13, 10523-10538 (2005). [CrossRef] [PubMed]
  3. M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10, 044009 (2005). [CrossRef]
  4. K. M. Yung, S. L. Lee, and J. M. Schmitt, "Phase-domain processing of optical coherence tomography images," J. Biomed. Opt. 4, 125-136 (1999). [CrossRef]
  5. M. Pircher, E. Gotzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
  6. D. C. Adler, T. H. Ko, and J. G. Fujimoto, "Speckle reduction in optical coherence tomography images by use of a spatially adaptive wavelet filter," Opt. Lett. 29, 2878-2880 (2004). [CrossRef]
  7. D. L. Marks, T. S. Ralston, and S. A. Boppart, "Speckle reduction by I-divergence regularization in optical coherence tomography," J. Opt. Soc. Am. A 22, 2366-2371 (2005). [CrossRef]
  8. J. M. Schmitt, "Array detection for speckle reduction in optical coherence microscopy," Phys. Med. Biol. 42, 1427-1439 (1997). [CrossRef] [PubMed]
  9. M. Bashkansky and J. Reintjes, "Statistics and reduction of speckle in optical coherence tomography," Opt. Lett. 25, 545-547 (2000). [CrossRef]
  10. N. Iftimia, B. E. Bouma, and G. J. Tearney, "Speckle reduction in optical coherence tomography by "path length encoded" angular compounding," J. Biomed. Opt. 8, 260-263 (2003). [CrossRef] [PubMed]
  11. J. M. Schmitt, S. H. Xiang, and K. M. Yung, "Speckle in optical coherence tomography," J. Biomed. Opt. 4, 95-105 (1999). [CrossRef]
  12. S. H. Yun, C. Boudoux, G. J. Tearney, and B. E. Bouma, "High-speed wavelength-swept semiconductor laser with a polygon-scanner-based wavelength filter," Opt. Lett. 28, 1981-1983 (2003). [CrossRef] [PubMed]
  13. R. A. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003). [CrossRef] [PubMed]
  14. B. Vakoc, S. Yun, J. de Boer, G. Tearney, and B. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13,5483-5493 (2005). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited