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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 7 — Jul. 17, 2006

Three-dimensional imaging by ultrahigh-speed axial-lateral parallel time domain optical coherence tomography

Yuuki Watanabe, Kazuhiko Yamada, and Manabu Sato  »View Author Affiliations


Optics Express, Vol. 14, Issue 12, pp. 5201-5209 (2006)
http://dx.doi.org/10.1364/OE.14.005201


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Abstract

We developed a method for obtaining three-dimensional images of biological tissues using axial-lateral parallel time domain optical coherence tomography (OCT) with an ultrahigh-speed complementary metal oxide semiconductor (CMOS) camera. The camera obtains a depth-resolved interference image using diffracted light as the reference beam and a linear illumination beam without axial and vertical scans. We can obtain the OCT images (512×512 pixels) at 1,500 frames per second by calculating two sequential images. A sample volume of 5.8×2.8×2.0 (x×y×z) mm3 (corresponding to 512×250×512 pixels) was imaged at six volumes per second in a horizontal mechanical scan. The experimental sensitivity was approximately 76 dB after 2×2-pixel binning. The system was successfully used to image the human finger in vivo.

© 2006 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.3180) Instrumentation, measurement, and metrology : Interferometry

ToC Category:
Imaging Systems

History
Original Manuscript: April 20, 2006
Revised Manuscript: May 12, 2006
Manuscript Accepted: May 18, 2006
Published: June 12, 2006

Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Yuuki Watanabe, Kazuhiko Yamada, and Manabu Sato, "Three-dimensional imaging by ultrahigh-speed axial-lateral parallel time domain optical coherence tomography," Opt. Express 14, 5201-5209 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-14-12-5201


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