OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 7 — Jul. 17, 2006

An extended cavity diode-pumped femtosecond Yb:KGW laser for applications in optical DNA sensor technology based on fluorescence lifetime measurements

Arkady Major, Virginijus Barzda, Paul A. E. Piunno, Sergei Musikhin, and Ulrich J. Krull  »View Author Affiliations


Optics Express, Vol. 14, Issue 12, pp. 5285-5294 (2006)
http://dx.doi.org/10.1364/OE.14.005285


View Full Text Article

Enhanced HTML    Acrobat PDF (140 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

A reliable and power-scalable extended cavity diode-pumped passively mode-locked Yb:KGW laser generating ~200 fs long pulses at a repetition rate of 15 MHz was developed and characterized. The laser delivered up to 150 mW of average power at fundamental wavelength of 1040 nm, corresponding to a pulse energy of 10 nJ. The laser radiation was frequency-doubled in a single pass configuration within a nonlinear BIBO crystal to produce femtosecond green radiation at 520 nm with peak power of ~200 W. The generated second harmonic served as an excitation source for an optical DNA biosensor based on fluorescence lifetime measurements obtained using the time-correlated single photon counting technique.

© 2006 Optical Society of America

OCIS Codes
(140.3480) Lasers and laser optics : Lasers, diode-pumped
(140.3580) Lasers and laser optics : Lasers, solid-state
(140.4050) Lasers and laser optics : Mode-locked lasers
(140.7090) Lasers and laser optics : Ultrafast lasers

ToC Category:
Lasers and Laser Optics

History
Original Manuscript: April 7, 2006
Revised Manuscript: May 12, 2006
Manuscript Accepted: May 20, 2006
Published: June 12, 2006

Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Arkady Major, Virginijus Barzda, Paul A. E. Piunno, Sergei Musikhin, and Ulrich J. Krull, "An extended cavity diode-pumped femtosecond Yb:KGW laser for applications in optical DNA sensor technology based on fluorescence lifetime measurements," Opt. Express 14, 5285-5294 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-14-12-5285


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. J. H. Watterson, S. Raha, C. C. Kotoris, C. C. Wust, F. Gharabaghi, S. C. Jantzi, N. K. Haynes, N. H. Gendron, U. J. Krull, A. E. Mackenzie and P. A. E. Piunno, "Rapid detection of single nucleotide polymorphisms associated with spinal muscular atrophy by use of a reusable fibre-optic biosensor," Nucl. Acids Res. 32, e18 (2004). [CrossRef] [PubMed]
  2. P. A. E. Piunno and U. J. Krull, "Trends in the development of nucleic acid biosensors for medical diagnostics," Anal. Bioanal. Chem. 381, 1004-1011 (2005). [CrossRef] [PubMed]
  3. J. Olmsted and D. R. Kearns, "Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids," Biochem. 16, 3647-3654 (1977). [CrossRef]
  4. R. Paschotta, J. Aus der Au, G. J. Spühler, F. Morier-Genoud, R.Hövel, M. Moser, S. Erhard, M. Karszewski, A. Giesen, and U. Keller, "Diode-pumped passively mode-locked lasers with high average power," Appl. Phys. B 70, S25-S31 (2000). [CrossRef]
  5. M. Ramaswamy, M. Ulman, J. Paye, and J. G. Fujimoto, "Cavity-dumped femtosecond Kerr-lens mode-locked Ti:A12O3 laser," Opt. Lett. 18, 1822-1824 (1993). [CrossRef] [PubMed]
  6. A. Killi, A. Steinmann, J. Dörring, U. Morgner, M. J. Lederer, D. Kopf, and C. Fallnich, "High-peak-power pulses from a cavity-dumped Yb:KY(WO4)2 oscillator," Opt. Lett. 30, 1891-1893 (2005). [CrossRef] [PubMed]
  7. N. H. Schiller, X. M. Zhao, X. C. Liang, L. M. Wang, and R. R. Alfano, "Compact picosecond Nd:glass mode-locked laser with variable cavity length from 5 to 21 m," Appl. Opt. 28, 946-948 (1989). [CrossRef] [PubMed]
  8. A. R. Libertun, R. Shelton, H. C. Kapteyn, and M. M. Murnane, "A 36 nJ-15.5 MHz extended-cavity Ti:sapphire oscillator," in Conference on Lasers and Electro-Optics, OSA Technical Digest (Optical Society of America, Washington DC, 1999), paper CThR3, pp. 469-470.
  9. A. M. KowaleviczJr., A. Tucay Zare, F. X. Kärtner, J. G. Fujimoto, S. Dewald, U. Morgner, V. Scheuer and G. Angelow, "Generation of 150-nJ pulses from a multiple-pass cavity Kerr-lens mode-locked Ti:Al2O3 oscillator," Opt. Lett. 28, 1597-1599 (2003). [CrossRef] [PubMed]
  10. V. Shcheslavskiy, V. V. Yakovlev, A. Ivanov, "High-energy self-starting femtosecond Cr4+:Mg2SiO4 oscillator operating at a low repetition rate," Opt. Lett. 26, 1999-2001 (2001). [CrossRef]
  11. R. P. Prasankumar, Y. Hirakawa, A. M. KowaleviczJr., F. X. Kaertner, and J. G. Fujimoto, "An extended cavity femtosecond Cr:LiSAF laser pumped by low cost diode lasers," Opt. Express 11, 1265-1269 (2003). [CrossRef] [PubMed]
  12. V. Z. Kolev, M. J. Lederer, B. Luther-Davies, and A. V. Rode, "Passive mode locking of a Nd:YVO4 laser with an extra-long optical resonator," Opt. Lett. 28, 1275-1277 (2003). [CrossRef] [PubMed]
  13. D. N. Papadopoulos, S. Forget, M. Delaigue, F. Druon, F. Balembois, and P. Georges, "Passively mode-locked diode-pumped Nd:YVO4 oscillator operating at an ultralow repetition rate," Opt. Lett. 28, 1838-1840 (2003). [CrossRef] [PubMed]
  14. G. I. Petrov, V. V. Yakovlev, N. I. Minkovski, "Broadband nonlinear optical conversion of a high-energy diode-pumped picosecond laser," Opt. Commun. 229, 441-445 (2004). [CrossRef]
  15. N. V. Kuleshov, A. A. Lagatsky, A. V. Podlipensky, V. P. Mikhailov, G. Huber, "Pulsed laser operation of Yb-doped KY(WO4)2 and KGd(WO4)2," Opt. Lett. 22, 1317-1319 (1997). [CrossRef]
  16. S. Lévêque-Fort, D. N. Papadopoulos, S. Forget, F. Balembois, and P. Georges, "Fluorescence lifetime imaging with a low-repetition-rate passively mode-locked diode-pumped Nd:YVO4 oscillator," Opt. Lett. 30, 168-170 (2005). [CrossRef] [PubMed]
  17. F. Brunner, G. J. Spühler, J. Aus der Au, L. Krainer, F. Morier-Genoud, R. Paschotta, N. Lichtenstein, S. Weiss, C. Harder, A. A. Lagatsky, A. Abdolvand, N. V. Kuleshov, and U. Keller, "Diode-pumped femtosecond Yb:KGd(WO4)2 laser with 1.1W average output," Opt. Lett. 25, 1119-1121 (2000). [CrossRef]
  18. A. Major, L. Giniunas, N. Langford, A. I. Ferguson, D. Burns, E. Bente, and R. Danielius, "Saturable Bragg reflector-based continuous-wave mode locking of Yb:KGd(WO4)2 laser," J. Mod. Opt. 49, 787-793 (2002). [CrossRef]
  19. A. Courjaud, N. Deguil, and F. Salin, "High power diode-pumped Yb:KGW ultrafast laser," in OSA Trends in Optics and Photonics (TOPS)73, Conference on Lasers and Electro-Optics, OSA Technical Digest (Optical Society of America, Washington DC, 2002), paper CThO3, pp. 501-502.
  20. G. Paunescu, J. Hein and R. Sauerbrey, "100-fs diode-pumped Yb:KGW mode-locked laser," Appl. Phys. B 79, 555-558 (2004). [CrossRef]
  21. A. Major, R. Cisek and V. Barzda, "Development of diode-pumped high average power continuous-wave and ultrashort pulse Yb:KGW lasers for nonlinear microscopy," in Commercial and Biomedical Applications of Ultrafast Lasers VI; J. Neev, S. Nolte, A. Heisterkamp, and C. B. Schaffer, eds. SPIE Proc. 6108, 189-196 (2006).
  22. Amplitude Systemes, http://www.amplitude-systemes.com/.
  23. U. Keller, K. J. Weingarten, F. X. Kärtner, D. Kopf, B. Braun, I. D. Jung, R. Fluck, C. Hönniger, N. Matuschek, and J . Aus der Au, "Semiconductor saturable absorber mirrors (SESAM’s) for femtosecond to nanosecond pulse generation in solid-state lasers," IEEE J. Sel. Top. Quantum Electron. 2, 435-453 (1996). [CrossRef]
  24. H. Hellwig, J. Liebertz, and L. Bohaty, "Exceptional large nonlinear optical coefficients in the monoclinic bismuth borate BiB3O6," Solid State Commun. 109, 249-251 (1999). [CrossRef]
  25. H. Hellwig, J. Liebertz, and L. Bohaty, "Linear optical properties of the monoclinic bismuth borate BiB3O6," J. Appl. Phys. 88, 240-244 (2000). [CrossRef]
  26. Z. Wang, B. Teng, K. Fu, X. Xu, R. Song, C. Du, H. Jiang, J. Wang, and Z. Shao, "Efficient second harmonic generation of pulsed laser radiation in BiB3O6 (BIBO) crystal with different phase matching directions," Opt. Commun. 202,217-220 (2002). [CrossRef]
  27. T. Harimoto, Y. Takeuchi, M. Fujita, "Spectral properties of second-harmonic generation at 800 nm in a BiB3O6 crystal," Opt. Express 12, 811-816 (2004). [CrossRef] [PubMed]
  28. M. Ghotbi, M. Ebrahim-Zadeh, A. Majchrowski, E. Michalski, and I. V. Kityk, "High-average-power femtosecond pulse generation in the blue using BiB3O6," Opt. Lett. 29, 2530-2532 (2004). [CrossRef] [PubMed]
  29. M. Ghotbi, and M. Ebrahim-Zadeh, "990 mW average power, 52% efficient, high-repetition-rate picosecond-pulse generation in the blue with BiB3O6," Opt. Lett. 30, 3395-3397 (2005). [CrossRef]
  30. D. V. O’Connor and D. Phillips, Time-Correlated Single Photon Counting (Academic, New York, 1984).
  31. <other>. P. A. E. Piunno, J. H. Watterson, C. Wust and U. J. Krull, "Considerations for the quantitative transduction of hybridization of immobilized DNA," Anal. Chim. Acta, 400, 73-89 1(999).</other>

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited