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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 12 — Dec. 18, 2006

Simulation of keratoconus observation in photorefraction

Ying-Ling Chen, B. Tan, K. Baker, J. W. L. Lewis, T. Swartz, Y. Jiang, and M. Wang  »View Author Affiliations

Optics Express, Vol. 14, Issue 23, pp. 11477-11485 (2006)

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In the recent years, keratoconus (KC) has increasingly gained attention due to its treatment options and to the popularity of keratorefractive surgery. This paper investigates the potential of identification of KC using photorefraction (PR), an optical technique that is similar to objective retinoscopy and is commonly used for large-scale ocular screening. Using personalized eye models of both KC and pre-LASIK patients, computer simulations were performed to achieve visualization of this ophthalmic measurement. The simulations are validated by comparing results to two sets of experimental measurements. These PR images show distinguishable differences between KC eyes and eyes that are either normal or ametropic. The simulation technique with personalized modeling can be extended to other ophthalmic instrument developments. It makes possible investigation with the least number of real human subjects. The application is also of great interest in medical training.

© 2006 Optical Society of America

OCIS Codes
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(330.4060) Vision, color, and visual optics : Vision modeling
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices

ToC Category:
Vision and color

Original Manuscript: September 11, 2006
Revised Manuscript: October 26, 2006
Manuscript Accepted: October 30, 2006
Published: November 13, 2006

Virtual Issues
Vol. 1, Iss. 12 Virtual Journal for Biomedical Optics

Ying-Ling Chen, B. Tan, K. Baker, J. W. L. Lewis, T. Swartz, Y. Jiang, and M. Wang, "Simulation of keratoconus observation in photorefraction," Opt. Express 14, 11477-11485 (2006)

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