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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 1 — Jan. 19, 2007

High-speed imaging of human retina in vivo with swept-source optical coherence tomography

H. Lim, M. Mujat, C. Kerbage, E. C. W. Lee, Y. Chen, Teresa C. Chen, and J. F. de Boer  »View Author Affiliations


Optics Express, Vol. 14, Issue 26, pp. 12902-12908 (2006)
http://dx.doi.org/10.1364/OE.14.012902


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Abstract

We present the first demonstration of human retinal imaging in vivo using optical frequency domain imaging (OFDI) in the 800-nm range. With 460-µW incident power on the eye, the sensitivity is 91 dB at maximum and >85 dB over 2-mm depth range. The axial resolution is 13 µm in air. We acquired images of retina at 43,200 depth profiles per second and a continuous acquisition speed of 84 frames/s (512 A-lines per frame) could be maintained over more than 2 seconds.

© 2006 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(140.3600) Lasers and laser optics : Lasers, tunable
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 29, 2006
Revised Manuscript: December 4, 2006
Manuscript Accepted: December 5, 2006
Published: December 25, 2006

Virtual Issues
Vol. 2, Iss. 1 Virtual Journal for Biomedical Optics

Citation
H. Lim, Teresa C. Chen, J. F. de Boer, M. Mujat, C. Kerbage, E. C. W. Lee, and Y. Chen, "High-speed imaging of human retina in vivo with swept-source optical coherence tomography," Opt. Express 14, 12902-12908 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-14-26-12902


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