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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 4 — Apr. 12, 2006

Optics InfoBase > Virtual Journal for Biomedical Optics > Volume 1 > Issue 4 > Page 1862

Automatic characterization and segmentation of human skin using three-dimensional optical coherence tomography

Yasuaki Hori, Yoshiaki Yasuno, Shingo Sakai, Masayuki Matsumoto, Tomoko Sugawara, Violeta Madjarova, Masahiro Yamanari, Shuichi Makita, Takeshi Yasui, Tsutomu Araki, Masahide Itoh, and Toyohiko Yatagai  »View Author Affiliations


Optics Express, Vol. 14, Issue 5, pp. 1862-1877 (2006)
http://dx.doi.org/10.1364/OE.14.001862


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Abstract

A set of fully automated algorithms that is specialized for analyzing a three-dimensional optical coherence tomography (OCT) volume of human skin is reported. The algorithm set first determines the skin surface of the OCT volume, and a depth-oriented algorithm provides the mean epidermal thickness, distribution map of the epidermis, and a segmented volume of the epidermis. Subsequently, an en face shadowgram is produced by an algorithm to visualize the infundibula in the skin with high contrast. The population and occupation ratio of the infundibula are provided by a histogram-based thresholding algorithm and a distance mapping algorithm. En face OCT slices at constant depths from the sample surface are extracted, and the histogram-based thresholding algorithm is again applied to these slices, yielding a three-dimensional segmented volume of the infundibula. The dermal attenuation coefficient is also calculated from the OCT volume in order to evaluate the skin texture. The algorithm set examines swept-source OCT volumes of the skins of several volunteers, and the results show the high stability, portability and reproducibilityof the algorithm.

© 2006 Optical Society of America

OCIS Codes
(100.6950) Image processing : Tomographic image processing
(110.4500) Imaging systems : Optical coherence tomography
(170.1870) Medical optics and biotechnology : Dermatology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 3, 2006
Revised Manuscript: February 20, 2006
Manuscript Accepted: February 27, 2006
Published: March 6, 2006

Virtual Issues
Vol. 1, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Yasuaki Hori, Yoshiaki Yasuno, Shingo Sakai, Masayuki Matsumoto, Tomoko Sugawara, Violeta Madjarova, Masahiro Yamanari, Shuichi Makita, Takeshi Yasui, Tsutomu Araki, Masahide Itoh, and Toyohiko Yatagai, "Automatic characterization and segmentation of human skin using three-dimensional optical coherence tomography," Opt. Express 14, 1862-1877 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-14-5-1862


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