Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction
Optics Express, Vol. 15, Issue 10, pp. 6200-6209 (2007)
http://dx.doi.org/10.1364/OE.15.006200
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Abstract
We present a novel method for rapidly acquiring optical coherence tomography (OCT) images at multiple backscattering angles. By angularly compounding these images, high levels of speckle reduction were achieved. Signal-to-noise ratio (SNR) improvements of 3.4 dB were obtained from a homogeneous tissue phantom, which was in good agreement with the predictions of a statistical model of speckle that incorporated the optical parameters of the imaging system. In addition, the fast acquisition rate of the system (10 kHz A-line repetition rate) allowed angular compounding to be performed in vivo without significant motion artifacts. Speckle-reduced OCT images of human dermis show greatly improved delineation of tissue microstructure.
© 2007 Optical Society of America
OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: February 13, 2007
Revised Manuscript: April 2, 2007
Manuscript Accepted: April 5, 2007
Published: May 4, 2007
Virtual Issues
Vol. 2, Iss. 6 Virtual Journal for Biomedical Optics
Citation
A. E. Desjardins, B. J. Vakoc, W. Y. Oh, S. M. Motaghiannezam, G. J. Tearney, and B. E. Bouma, "Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction," Opt. Express 15, 6200-6209 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-10-6200
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References
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