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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 8 — Aug. 10, 2007

Fiber-optic confocal microscope using a MEMS scanner and miniature objective lens

Hyun-Joon Shin, Mark C. Pierce, Daesung Lee, Hyejun Ra, Olav Solgaard, and Rebecca Richards-Kortum  »View Author Affiliations


Optics Express, Vol. 15, Issue 15, pp. 9113-9122 (2007)
http://dx.doi.org/10.1364/OE.15.009113


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Abstract

We designed and constructed a single-fiber-optic confocal microscope (SFCM) with a microelectromechanical system (MEMS) scanner and a miniature objective lens. Axial and lateral resolution values for the system were experimentally measured to be 9.55 µm and 0.83 µm respectively, in good agreement with theoretical predictions. Reflectance images were acquired at a rate of 8 frames per second, over a 140 µm×70 µm field-of-view. In anticipation of future applications in oral cancer detection, we imaged ex vivo and in vivo human oral tissue with the SFCM, demonstrating the ability of the system to resolve cellular detail.

© 2007 Optical Society of America

OCIS Codes
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 16, 2007
Revised Manuscript: June 7, 2007
Manuscript Accepted: June 8, 2007
Published: July 10, 2007

Virtual Issues
Vol. 2, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Hyun-Joon Shin, Mark C. Pierce, Daesung Lee, Hyejun Ra, Olav Solgaard, and Rebecca Richards-Kortum, "Fiber-optic confocal microscope using a MEMS scanner and miniature objective lens," Opt. Express 15, 9113-9122 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-15-9113


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