The resolution of optical traps created by Light Induced Dielectrophoresis (LIDEP)

doi:10.1364/OE.15.012619

The resolution of optical traps created by Light Induced Dielectrophoresis (LIDEP)

S. L. Neale, M. Mazilu, J. I. B. Wilson, K. Dholakia, and T. F. Krauss »View Author Affiliations

Optics Express, Vol. 15, Issue 20, pp. 12619-12626 (2007)
http://dx.doi.org/10.1364/OE.15.012619

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Abstract

Light induced dielectrophoresis (LIDEP) is a variant of the dielectrophoresis (DEP) mechanism that has been used for some time to manipulate particles in a microfluidic environment. Rather than relying on lithographically created contacts to generate the required electrical fields, the electrical contacts in LIDEP are created through the selective illumination of a photoconductor. The key question we address is how microscopic traps created via LIDEP compare to optical traps based on the gradient force, in terms of power required and trap stiffness achieved, as well as the size resolution of such a trap. We highlight the complex interplay between optical power and resolution with electrical parameters, such as the electrical resistance and applied AC Voltage. We show that for a spotsize of five micrometres and larger, particles can indeed be trapped with low power. We use trap stiffness per mW to compare LIDEP with an optical trap and show that our system is 470± 94 times stiffer per mW than a conventional optical trap, with no loss of resolution. We also discuss the difficulties of achieving trapping at smaller spot sizes, and that the sub-micron resolution possible with gradient force trapping is very difficult to realise with LIDEP.

OCIS Codes
(140.7010) Lasers and laser optics : Laser trapping
(250.0250) Optoelectronics : Optoelectronics

ToC Category:
Trapping

History
Original Manuscript: July 19, 2007
Revised Manuscript: September 11, 2007
Manuscript Accepted: September 11, 2007
Published: September 17, 2007

Virtual Issues
Vol. 2, Iss. 11 Virtual Journal for Biomedical Optics

Citation
S. L. Neale, M. Mazilu, J. I. B. Wilson, K. Dholakia, and T. F. Krauss, "The resolution of optical traps created by Light Induced Dielectrophoresis (LIDEP)," Opt. Express 15, 12619-12626 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-20-12619

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References

H. A. Pohl, Dielectrophoresis (Cambridge University Press, Cambridge, 1978).
P. Y. Chiou, A. T. Ohta and M. C. Wu, "Massively parallel Manipulation of single cells and microparticles using optical images," Nature 436, 370-372 (2005). [CrossRef] [PubMed]
P. Y. Chiou, A. T. Ohta and M. C. Wu, "Toward all optical lab-on-a-chip system: optical manipulation of both microfluid and microscopic particles," Proc. SPIE 5514, 73-81 (2004). [CrossRef]
A. T. Ohta, P. Y. Chiou and M. C. Wu, "Optically-controlled manipulation of live cells using optoelectronic t tweezers," Proc. SPIE 6326, 632617 (2006). [CrossRef]
K. Dholakia and P Reece, "Optical micromanipulation takes hold," Nano Today 1, 18 (2006). [CrossRef]
A. T. Ohta, P. Y. Chiou, H. L. Phan, S. W. Sherwood, J. M. Yang, A. N. K. Lau, H. Y. Hsu, A. Jamshidi, and M. C. Wu, "Optically controlled cell discrimination and trapping using Optoelectronic Tweezers," IEEE J. Sel. Top. Quantum Electron. 13, 235-243 (2007). [CrossRef]
Y. S. Lu, Y. P. Huang, J. A. Yeh, C. Lee and Y. H. Chang, "Controllability of non-contact manipulation by image dielectrophoresis," Opt. Quantum Electron. 37, 1385-1395 (2005). [CrossRef]
K. Svoboda and S. M. Block, "Biological applications of optical forces," Annu. Rev. Biophys. Biomol. Struct. 23, 247-285 (1994). [CrossRef] [PubMed]
M. P. Hughes, Nanoelectromechanics in Engineering and Biology, (CRC Press, 2003).
Particle trapping software developed by Graham Milne based on the pattern matching capabilities built into LabVIEW.

Block, S. M.
Chang, Y. H.
Chiou, P. Y.
Dholakia, K.
Hsu, H. Y.
Huang, Y. P.
Jamshidi, A.
Lau, A. N. K.
Lee, C.
Lu, Y. S.
Ohta, A. T.
Phan, H. L.
Reece, P
Sherwood, S. W.
Svoboda, K.
Wu, M. C.
Yang, J. M.
Yeh, J. A.

Annu. Rev. Biophys. Biomol. Struct.

K. Svoboda and S. M. Block, "Biological applications of optical forces," Annu. Rev. Biophys. Biomol. Struct. 23, 247-285 (1994). [CrossRef] [PubMed]

IEEE J. Sel. Top. Quantum Electron.

A. T. Ohta, P. Y. Chiou, H. L. Phan, S. W. Sherwood, J. M. Yang, A. N. K. Lau, H. Y. Hsu, A. Jamshidi, and M. C. Wu, "Optically controlled cell discrimination and trapping using Optoelectronic Tweezers," IEEE J. Sel. Top. Quantum Electron. 13, 235-243 (2007). [CrossRef]

Nano Today

K. Dholakia and P Reece, "Optical micromanipulation takes hold," Nano Today 1, 18 (2006). [CrossRef]

Nature

P. Y. Chiou, A. T. Ohta and M. C. Wu, "Massively parallel Manipulation of single cells and microparticles using optical images," Nature 436, 370-372 (2005). [CrossRef] [PubMed]

Opt. Quantum Electron.

Y. S. Lu, Y. P. Huang, J. A. Yeh, C. Lee and Y. H. Chang, "Controllability of non-contact manipulation by image dielectrophoresis," Opt. Quantum Electron. 37, 1385-1395 (2005). [CrossRef]

Proc. SPIE

P. Y. Chiou, A. T. Ohta and M. C. Wu, "Toward all optical lab-on-a-chip system: optical manipulation of both microfluid and microscopic particles," Proc. SPIE 5514, 73-81 (2004). [CrossRef]
A. T. Ohta, P. Y. Chiou and M. C. Wu, "Optically-controlled manipulation of live cells using optoelectronic t tweezers," Proc. SPIE 6326, 632617 (2006). [CrossRef]

Other

H. A. Pohl, Dielectrophoresis (Cambridge University Press, Cambridge, 1978).
M. P. Hughes, Nanoelectromechanics in Engineering and Biology, (CRC Press, 2003).
Particle trapping software developed by Graham Milne based on the pattern matching capabilities built into LabVIEW.

2007, Ohta, IEEE J. Sel. Top. Quantum Electron.
2006, Ohta, Proc. SPIE
2006, Dholakia, Nano Today
2005, Chiou, Nature
2005, Lu, Opt. Quantum Electron.
2004, Chiou, Proc. SPIE
1994, Svoboda, Annu. Rev. Biophys. Biomol. Struct.

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