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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 11 — Nov. 26, 2007

Optics InfoBase > Virtual Journal for Biomedical Optics > Volume 2 > Issue 11 > Page 14482

Portable, large-bandwidth time-resolved system for diffuse optical spectroscopy

Andrea Bassi, Andrea Farina, Cosimo D'Andrea, Antonio Pifferi, Gianluca Valentini, and Rinaldo Cubeddu  »View Author Affiliations


Optics Express, Vol. 15, Issue 22, pp. 14482-14487 (2007)
http://dx.doi.org/10.1364/OE.15.014482


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Abstract

We report the development of a compact time-resolved system for the measurement of the optical properties of highly scattering media over a bandwidth of 600–1000 nm. The instrument is based on a fiber laser generating supercontinuum radiation, that is spectrally dispersed and sequentially used to illuminate the sample. A single photon avalanche photo-diode in combination with time correlated single-photon counting is used to recover the time-dispersion curve at each wavelength, both fitted by the diffusion equation. Transmittance measurements performed on calibrated epoxy phantoms and in-vivo on female breast are presented, showing good agreement with previous reports.

© 2007 Optical Society of America

OCIS Codes
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(300.6500) Spectroscopy : Spectroscopy, time-resolved

ToC Category:
Spectroscopy

History
Original Manuscript: July 13, 2007
Revised Manuscript: September 6, 2007
Manuscript Accepted: September 12, 2007
Published: October 19, 2007

Virtual Issues
Vol. 2, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Andrea Bassi, Andrea Farina, Cosimo D'Andrea, Antonio Pifferi, Gianluca Valentini, and Rinaldo Cubeddu, "Portable, large-bandwidth time-resolved system for diffuse optical spectroscopy," Opt. Express 15, 14482-14487 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-22-14482


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References

  1. P. Taroni, D. Comelli, A. Pifferi, A. Torricelli, R. Cubeddu, "Absorption of collagen: effects on the estimate of breast composition and related diagnostic implications," J. Biomed. Opt. 12, 14021 (2007). [CrossRef]
  2. S. Andersson-Engels, R. Berg, A. Persson, and S. Svanberg, "Multispectral tissue characterization with timeresolved detection of diffusely scattered white light," Opt. Lett. 18, 1697-1699 (1993). [CrossRef] [PubMed]
  3. A. Pifferi, A. Torricelli, P. Taroni, D. Comelli, A. Bassi, R. Cubeddu, "Fully automated time domain spectrometer for the absorption and scattering characterization of diffusive media," Rev. Sci. Instrum. 78, 053103 (2007). [CrossRef] [PubMed]
  4. R. M. P. Doornbos, R. Lang, M. C. Aalders, F. W. Cross, and H. J. C. M. Sterenborg, "The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steadystate diffuse reflectance spectroscopy," Phys. Med. Biol. 44, 967-981 (1999). [CrossRef] [PubMed]
  5. F. Bevilacqua, A. J. Berger, A. E. Cerussi, D. Jakubowski, and B. J. Tromberg, "Broadband absorption spectroscopy in turbid media by combined frequency-domain and steady-state methods," Appl. Opt. 39, 6498-6507 (2000). [CrossRef]
  6. J. K. Ranka, R. S. Windeler, and A. J. Stentz, "Visible continuum generation in air-silica microstructure optical fibers with anomalous dispersion at 800 nm," Opt. Lett. 25, 25-27 (2000). [CrossRef]
  7. S. Cova, M. Ghioni, A. Lotito, I. Rech, and F. Zappa, "Evolution and prospects for single-photon avalanche diodes and quenching circuits," J. Mod. Opt. 51, 1267-1288 (2004).
  8. A. Bassi, J. Swartling, C. D’Andrea, A. Pifferi, A. Torricelli, and R. Cubeddu, "Time-resolved spectrophotometer for turbid media based on supercontinuum generation in a photonic crystal fiber," Opt. Lett. 29, 2405-2407 (2004). [CrossRef] [PubMed]
  9. C. Abrahamsson, T. Svensson, S. Svanberg, S. Andersson-Engels, J. Johansson, and S. Folestad, "Time and wavelength resolved spectroscopy of turbid media using light continuum generated in a crystal fiber," Opt. Express 12, 4103-4112 (2004). [CrossRef] [PubMed]
  10. T. Binzoni, C. Courvoisier, R. Giust, G. Tribillon, T. Gharbi, J. C. Hebden, T. S. Leung, J. Roux, and D. T. Delpy, "Anisotropic photon migration in human skeletal muscle," Phys. Med. Biol. 51, N79-N90 (2006). [CrossRef] [PubMed]
  11. R. C. Haskell, L. O. Svaasand, T.-T. Tsay, T.-C. Feng, M. S. McAdams, and B. J. Tromberg, "Boundary conditions for the diffusion equation in radiative transfer," J. Opt. Soc. Am. A 11, 2727-2741 (1994). [CrossRef]
  12. A. Pifferi, A. Torricelli, A. Bassi, P. Taroni, R. Cubeddu, H. Wabnitz, D. Grosenick, M. Moller, R. Macdonald, J. Swartling, T. Svensson, S. Andersson-Engels, R. L. P. van Veen, H. J. C. M. Sterenborg, J. M. Tualle, H. L. Nghiem, S. Avriller, M. Whelan, and H. Stamm, "Performance assessment of photon migration instruments: the MEDPHOT protocol," Appl. Opt. 44, 2104-2114, (2005). [CrossRef] [PubMed]

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