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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 1 — Jan. 29, 2008

Simultaneous SLO/OCT imaging of the human retina with axial eye motion correction

Michael Pircher, Bernhard Baumann, Erich Götzinger, Harald Sattmann, and Christoph K. Hitzenberger  »View Author Affiliations


Optics Express, Vol. 15, Issue 25, pp. 16922-16932 (2007)
http://dx.doi.org/10.1364/OE.15.016922


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Abstract

It has been shown that transversal scanning (or en-face) optical coherence tomography (TS-OCT) represents an imaging modality capable to record high isotropic resolution images of the human retina in vivo. However, axial eye motion still remains a challenging problem of this technique. In this paper we introduce a novel method to compensate for this eye motion. An auxiliary spectral domain partial coherence interferometer (SD-PCI) was integrated into an existing TS-OCT system and used to measure accurately the position of the cornea. A light source emitting at 1310nm was used in the additional interferometer which enabled a nearly loss free coupling of the two measurement beams via a dichroic mirror. The recorded corneal position was used to drive an additional voice coil translation stage in the reference arm of the TS-OCT system to correct for axial eye motion. Currently, the correction can be performed with an update rate of ~200Hz. The TS-OCT instrument is operated with a line scan rate of 4000 transversal lines per second which enables simultaneous SLO/OCT imaging at a frame rate of 40fps. 3D data of the human retina with isotropic high resolution, that was sufficient to visualize the human cone mosaic in vivo, is presented.

© 2007 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 2, 2007
Revised Manuscript: November 28, 2007
Manuscript Accepted: December 3, 2007
Published: December 4, 2007

Virtual Issues
Vol. 3, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Michael Pircher, Bernhard Baumann, Erich Götzinger, Harald Sattmann, and Christoph K. Hitzenberger, "Simultaneous SLO/OCT imaging of the human retina with axial eye motion correction," Opt. Express 15, 16922-16932 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-25-16922


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