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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 1 — Jan. 29, 2008

Detection of multiple scattering in optical coherence tomography using the spatial distribution of Stokes vectors

Steven G. Adie, Timothy R. Hillman, and David D. Sampson  »View Author Affiliations


Optics Express, Vol. 15, Issue 26, pp. 18033-18049 (2007)
http://dx.doi.org/10.1364/OE.15.018033


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Abstract

Multiple scattering is one of the main degrading influences in optical coherence tomography, but to date its presence in an image can only be indirectly inferred. We present a polarization-sensitive method that shows the potential to detect it more directly, based on the degree to which the detected polarization state at any given image point is correlated with the mean state over the surrounding region. We report the validation of the method in microsphere suspensions, showing a strong dependence of the degree of correlation upon the extent to which multiply scattered light is coherently detected. We demonstrate the method’s utility in various tissues, including chicken breast ex vivo and human skin and nailfold in vivo.

© 2007 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(260.5430) Physical optics : Polarization
(290.1350) Scattering : Backscattering
(290.4210) Scattering : Multiple scattering

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 5, 2007
Revised Manuscript: December 13, 2007
Manuscript Accepted: December 14, 2007
Published: December 18, 2007

Virtual Issues
Vol. 3, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Steven G. Adie, Timothy R. Hillman, and David D. Sampson, "Detection of multiple scattering in optical coherence tomography using the spatial distribution of Stokes vectors," Opt. Express 15, 18033-18049 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-26-18033


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