OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 5 — May. 17, 2007

Improving depth resolution of diffuse optical tomography with a layer-based sigmoid adjustment method

Qing Zhao, Lijun Ji, and Tianzi Jiang  »View Author Affiliations


Optics Express, Vol. 15, Issue 7, pp. 4018-4029 (2007)
http://dx.doi.org/10.1364/OE.15.004018


View Full Text Article

Enhanced HTML    Acrobat PDF (188 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Diffuse optical tomography (DOT) has much lower sensitivity in deep tissues than in superficial tissues, which leads to poor depth resolution. In this paper, a layer-based sigmoid adjustment (LSA) method is proposed for reducing sensitivity contrast in the depth dimension. Using this method, differences in image quality between layers can be effectively reduced. As a result, positioning errors of less than 3 mm can be obtained in the depth dimension for all depths from -1 cm to -3 cm.

© 2007 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 28, 2006
Revised Manuscript: February 22, 2007
Manuscript Accepted: February 22, 2007
Published: April 2, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Qing Zhao, Lijun Ji, and Tianzi Jiang, "Improving depth resolution of diffuse optical tomography with a layer-based sigmoid adjustment method," Opt. Express 15, 4018-4029 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-15-7-4018


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. F. Jobsis, "Non-invasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory Parameters," Science 198, 1264-1267 (1977). [CrossRef] [PubMed]
  2. M. A. Franceschini, V. Toronov, M. E. Filiaci, and E. Gratton, "On-line optical imaging of the human brain with 160-ms temporal resolution," Opt. Express 6, 49-57 (2000). [CrossRef] [PubMed]
  3. S. Fantini, M. A. Fanceschini, and E. Gratton, "Non-invasive optical mapping of the piglet brain in real time," Opt. Express 4, 308-314 (1999). [CrossRef] [PubMed]
  4. G. Taga, Y. Konishi, A. Maki, T. Tachibana, M. Fujiwara, and H. Koizumi, "Spontaneous oscillation of oxy- and deoxy- hemoglobin changes with a phase difference throughout the occipital cortex of newborn infants observed using non-invasive optical topography," Neurosci. Lett. 282, 101-104 (2000). [CrossRef] [PubMed]
  5. V. Ntziachristos, and B. Chance, "Probing physiology and molecular function using optical imaging: applications to breast cancer," Breast Cancer Res. 3, 41-46 (2001). [CrossRef] [PubMed]
  6. A. M. Siegel, J. J. A. Marota, and D. A. Boas, "Design and evaluation of a continuous-wave diffuse optical tomography system," Opt. Express 4, 287-298 (1999). [CrossRef] [PubMed]
  7. S. R. Hintz, D. A. Benaron, A. M. Siegel, A. Zourabian, D. K. Stevenson, and D. A. Boas, "Bedside functional imaging of the premature infant brain during passive motor activation," J. Perinat. Med. 29, 335-343 (2001). [PubMed]
  8. A. Bluestone, G. Abdoulaev, C. Schmitz, R. Barbour, and A. Hielscher, "Three-dimensional optical tomography of hemodynamics in the human head," Opt. Express 9, 272-286 (2001). [CrossRef] [PubMed]
  9. E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, "Time resolved optical tomography of the human forearm," Phys. Med. Biol. 46, 1117-1130 (2001). [CrossRef] [PubMed]
  10. D. A. Boas, J. P. Culver, J. Stott, and A. K. Dunn, "Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult head," Opt. Express 10, 159-170 (2002). [PubMed]
  11. E. Okada, and D. T. Delpy, "Near-infrared light propagation in an adult head model. I. Modeling of low-level scattering in the cerebrospinal fluid layer," Appl. Opt. 42, 2906-2914 (2003). [CrossRef] [PubMed]
  12. E. Okada, and D. T. Delpy, "Near-infrared light propagation in an adult head model. II. Modeling of low-level scattering in the cerebrospinal fluid layer," Appl. Opt. 42, 2915-2922 (2003). [CrossRef] [PubMed]
  13. D. A. Boas, and A. M. Dale, "Simulation study of magnetic resonance imaging-guided cortically constrained diffuse optical tomography of human brain function," Appl. Opt. 44, 1957-1968 (2005) [CrossRef] [PubMed]
  14. A. Kienle, M. S. Patterson, N. Dognitz, R. Bays, G. Wagnieres, and H. van den Bergh, "Noninvasive determination of the optical properties of two-layered turbid media," Appl. Opt. 37, 779-791 (1998). [CrossRef]
  15. J. Steinbrink, H. Wabnitz, H. Obrig, A. Villringer, and H. Rinneberg, "Determining changes in NIR absorption using a layered model of the human head," Phys. Med. Biol. 46, 879-896 (2001). [CrossRef] [PubMed]
  16. M. Kohl-Bareis, H. Obrig, J. Steinbrink, J. Malak, K. Uludag, and A. Villringer, "Noninvasive monitoring of cerebral blood flow by a dye bolus method: separation of brain from skin and skull signals," J. Biomed. Opt. 7, 464-470 (2002). [CrossRef] [PubMed]
  17. B. W. Pogue, and K. D. Paulsen, "High-resolution near-infrared tomographic imaging simulations of the rat cranium by use of a priori magnetic resonance imaging structural information," Opt. Lett. 23, 1716-1718 (1998). [CrossRef]
  18. B. W. Pogue, T. O. McBride, J. Prewitt, U. L. Osterberg, and K. D. Paulsen, "Spatially variant regularization improves diffuse optical tomography," Appl. Opt. 38, 2950-2961 (1999). [CrossRef]
  19. J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003). [CrossRef] [PubMed]
  20. Q. Zhao, L. Ji, and T. Z. Jiang, "Improving performance of reflectance diffuse optical imaging using a multicentered mode," J. Biomed. Opt. 11, (2006) (in press). [CrossRef] [PubMed]
  21. S. R. Arridge, "Optical tomography in medical imaging," Inverse Probl. Eng. 15, R41-R93 (1999). [CrossRef]
  22. X. Cheng, and D. A. Boas, "Diffuse optical reflectance tomography with continuous-wave illumination," Opt. Express 3, 118-123 (1998). [CrossRef] [PubMed]
  23. D. A. Boas, A. M. Dale, and M. A. Franceschini, "Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy," NeuroImage 23, 275-288 (2004). [CrossRef]
  24. D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, "Estimation of optical pathlength through tissue from direct time of flight measurement," Phys. Med. Biol. 33, 1433-1442 (1988). [CrossRef] [PubMed]
  25. S. R. Arridge, "Optical tomography in medical imaging," Inverse Probl. Eng. 15, R41-R93 (1999). [CrossRef]
  26. D. A. Boas, A. M. Dale, and M. A. Franceschini, "Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy," NeuroImage 23, 275-288 (2004). [CrossRef]
  27. L. Wu, "A parameter choice method for Tikhonov regularization," Electron. Trans. Numer. Anal. 16, 107-128 (2003).
  28. P. C. Hansen, and D. O’Leary, "The Use of the L-Curve in the Regularization of Discrete Ill-Posed Problems," SIAM J. Sci. Comput. 14, 1487-1503 (1993). [CrossRef]
  29. X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, and H. Dehghani, "Automated region detection based on the contrast-to-noise ratio in near-infrared tomography," Appl. Opt. 43, 1053-1062 (2004). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited