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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 6 — Jun. 17, 2008

Super-resolution via iterative phase retrieval for blurred and saturated biological images

Eran Gur, Vassilios Sarafis, Igor Falat, Frantisek Vacha, Martin Vacha, and Zeev Zalevsky  »View Author Affiliations

Optics Express, Vol. 16, Issue 11, pp. 7894-7903 (2008)

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One of the most fascinating problems addressed today is retrieving high-resolution data of blurred images obtained from biological objects. In most cases the research relays either on a priory knowledge of the image nature or a large number of images (either of the same object or of different objects obtained by the same imaging setup). If saturation is added to the blurring, most algorithms fail to sharpen the image and in some cases researchers decline to use such images as an input. In this work a single captured blurred and saturated image is given with no a priori knowledge except of the fact that the primary blurring is due to defocused imaging setup. The authors suggest a novel three-stage approach for retrieving higher resolution data from the intensity distribution of the blurred and saturated image. The core of the process is the phase retrieval algorithm suggested by Gerchberg and Saxton in 1972. The new method is explained in details and the algorithm is tested numerically and experimentally on several images to show the improvement in the sharpness of the spatial details.

© 2008 Optical Society of America

OCIS Codes
(100.3010) Image processing : Image reconstruction techniques
(100.6640) Image processing : Superresolution
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(110.1455) Imaging systems : Blind deconvolution

ToC Category:
Image Processing

Original Manuscript: November 9, 2007
Revised Manuscript: December 24, 2007
Manuscript Accepted: January 10, 2008
Published: May 19, 2008

Virtual Issues
Vol. 3, Iss. 6 Virtual Journal for Biomedical Optics

Eran Gur, Vassilios Sarafis, Igor Falat, Frantisek Vacha, Martin Vacha, and Zeev Zalevsky, "Super-resolution via iterative phase retrieval for blurred and saturated biological images," Opt. Express 16, 7894-7903 (2008)

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