Optics InfoBase > Virtual Journal for Biomedical Optics > Volume 3 > Issue 9 > Page 12350
Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform
Yuankai K. Tao, Anjul M. Davis, and Joseph A. Izatt »View Author Affiliations
Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA
*Corresponding author: yt13@duke.edu
Optics Express, Vol. 16, Issue 16, pp. 12350-12361 (2008)
http://dx.doi.org/10.1364/OE.16.012350
View Full Text Article
Enhanced HTML
Acrobat PDF (464 KB)
Abstract
We demonstrate in vivo volumetric bidirectional blood flow imaging in animal models using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image half-planes, enabling volumetric bidirectional flow mapping without manual segmentation.
© 2008 Optical Society of America
OCIS Codes
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: May 16, 2008
Revised Manuscript: July 15, 2008
Manuscript Accepted: July 17, 2008
Published: August 1, 2008
Virtual Issues
Vol. 3, Iss. 9 Virtual Journal for Biomedical Optics
Citation
Yuankai K. Tao, Anjul M. Davis, and Joseph A. Izatt, "Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform," Opt. Express 16, 12350-12361 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-16-16-12350
Sort: Author | Year | Journal | Reset
References
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time Domain Optical Coherence Tomography," Opt. Express 16, 6008 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-9-6008 [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- R. A. Leitgeb, R. Michaely, T. Lasser, and S. C. Sekhar, "Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning," Opt Lett. 32, 3453 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3453 [CrossRef]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- R. K. Wang, "In vivo full range complex Fourier domain optical coherence tomography," Appl. Phys. Lett. 90, 054103 (2007).
- B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, "Full range complex spectral domain optical coherence tomography without additional phase shifters," Opt. Express 15, 13375 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-13375 [CrossRef] [PubMed]
- L. An, and R. K. Wang, "Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography," Opt Lett. 32, 3423 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3423 [CrossRef]
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- R. K. Wang, S. L. Jacques, Z. Ma, S. Hurst, S. R. Hanson, and A. Gruber, "Three dimensional optical angiography," Opt. Express 15, 4083 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-7-4083 [CrossRef] [PubMed]
- A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-2-408 [CrossRef] [PubMed]
- M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- V. Hamburger, and H. L. Hamilton, "A series of normal stages in the development of the chick embryo," J. Morphology 88, 54 (1951). [CrossRef]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- L. An, and R. K. Wang, "Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography," Opt Lett. 32, 3423 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3423 [CrossRef]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-2-408 [CrossRef] [PubMed]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time Domain Optical Coherence Tomography," Opt. Express 16, 6008 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-9-6008 [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, "Full range complex spectral domain optical coherence tomography without additional phase shifters," Opt. Express 15, 13375 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-13375 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- V. Hamburger, and H. L. Hamilton, "A series of normal stages in the development of the chick embryo," J. Morphology 88, 54 (1951). [CrossRef]
- V. Hamburger, and H. L. Hamilton, "A series of normal stages in the development of the chick embryo," J. Morphology 88, 54 (1951). [CrossRef]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, "Full range complex spectral domain optical coherence tomography without additional phase shifters," Opt. Express 15, 13375 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-13375 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time Domain Optical Coherence Tomography," Opt. Express 16, 6008 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-9-6008 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- R. A. Leitgeb, R. Michaely, T. Lasser, and S. C. Sekhar, "Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning," Opt Lett. 32, 3453 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3453 [CrossRef]
- A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-2-408 [CrossRef] [PubMed]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-2-408 [CrossRef] [PubMed]
- R. A. Leitgeb, R. Michaely, T. Lasser, and S. C. Sekhar, "Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning," Opt Lett. 32, 3453 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3453 [CrossRef]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, "Full range complex spectral domain optical coherence tomography without additional phase shifters," Opt. Express 15, 13375 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-13375 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- R. K. Wang, S. L. Jacques, Z. Ma, S. Hurst, S. R. Hanson, and A. Gruber, "Three dimensional optical angiography," Opt. Express 15, 4083 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-7-4083 [CrossRef] [PubMed]
- R. K. Wang, "In vivo full range complex Fourier domain optical coherence tomography," Appl. Phys. Lett. 90, 054103 (2007).
- L. An, and R. K. Wang, "Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography," Opt Lett. 32, 3423 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3423 [CrossRef]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time Domain Optical Coherence Tomography," Opt. Express 16, 6008 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-9-6008 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
Appl. Opt.
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
Appl. Phys. Lett.
- R. K. Wang, "In vivo full range complex Fourier domain optical coherence tomography," Appl. Phys. Lett. 90, 054103 (2007).
Circulation
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
J. Biomedical Opt.
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
J. Biomedical Opt..
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
J. Morphology
- V. Hamburger, and H. L. Hamilton, "A series of normal stages in the development of the chick embryo," J. Morphology 88, 54 (1951). [CrossRef]
Journal of Biomedical Optics
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
Ophthalmology
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
Opt Lett
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
Opt Lett.
- L. An, and R. K. Wang, "Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography," Opt Lett. 32, 3423 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3423 [CrossRef]
Opt. Commun.
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
Opt. Express
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time Domain Optical Coherence Tomography," Opt. Express 16, 6008 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-9-6008 [CrossRef] [PubMed]
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, "Full range complex spectral domain optical coherence tomography without additional phase shifters," Opt. Express 15, 13375 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-20-13375 [CrossRef] [PubMed]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- R. K. Wang, S. L. Jacques, Z. Ma, S. Hurst, S. R. Hanson, and A. Gruber, "Three dimensional optical angiography," Opt. Express 15, 4083 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-7-4083 [CrossRef] [PubMed]
- A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-2-408 [CrossRef] [PubMed]
- M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- E. Gotzinger, M. Pircher, R. A. Leitgeb, and C. K. Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-583 [CrossRef] [PubMed]
- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822 (2004). http://www.opticsexpress.org/abstract.cfm?id=81308 [CrossRef] [PubMed]
Opt. Lett.
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- R. A. Leitgeb, R. Michaely, T. Lasser, and S. C. Sekhar, "Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning," Opt Lett. 32, 3453 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3453 [CrossRef]
Optics Express
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
2008, Szkulmowski, Opt. Express
- S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1-mu m spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye," Opt. Express 16, 8406 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-12-8406 [CrossRef] [PubMed]
- B. S. Sorg, M. E. Hardee, N. Agarwal, B. J. Moeller, and M. W. Dewhirst, "Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors," J. Biomedical Opt. 13, (2008). [CrossRef] [PubMed]
- R. K. Wang, "In vivo full range complex Fourier domain optical coherence tomography," Appl. Phys. Lett. 90, 054103 (2007).
- L. An, and R. K. Wang, "Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography," Opt Lett. 32, 3423 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-23-3423 [CrossRef]
- A. Mariampillai, B. A. Standish, N. R. Munce, C. Randall, G. Liu, J. Y. Jiang, A. E. Cable, I. A. Vitkin, and V. X. D. Yang, "Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system," Optics Express 15, 1627 (2007). http://www.opticsinfobase.org/abstract.cfm?id=127228 [CrossRef] [PubMed]
- Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomedical Opt. 12, 041215 (2007). [CrossRef] [PubMed]
- B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomedical Opt. 12, 041214 (2007). [CrossRef] [PubMed]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 8 (2006). [CrossRef] [PubMed]
- A. H. Bachmann, R. A. Leitgeb, and T. Lasser, "Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution," Opt. Express 14, 1487 (2006). nfobase.org/abstract.cfm?URI=oe-14-4-1487">http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-4-1487 [CrossRef] [PubMed]
- M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt Lett 30, 1162 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-18-2183 [CrossRef] [PubMed]
- A. M. Davis, M. A. Choma, and J. A. Izatt, "Heterodyne swept-source optical coherence tomography for complete complex conjugate ambiguity removal," J. Biomedical Opt. 10, (2005). [CrossRef] [PubMed]
- J. Zhang, J. S. Nelson, and Z. P. Chen, "Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator," Opt. Lett. 30, 147 (2005). http://www.opticsinfobase.org/abstract.cfm?URI=ol-30-2-147 [CrossRef] [PubMed]
- L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 6 (2004). [CrossRef]
- N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Optics Express 12, 10 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-3-367 [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-Resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404 (2004). http://www.opticsinfobase.org/abstract.cfm?URI=oe-12-11-2404. [CrossRef] [PubMed]
- R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-23-3116 [CrossRef] [PubMed]
- B. R. White, M. C. Pierce, N. A. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. De Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 8 (2003). http://www.opticsinfobase.org/abstract.cfm?URI=oe-11-25-3490 [CrossRef] [PubMed]
- T. M. Yelbuz, M. A. Choma, L. Thrane, M. L. Kirby, and J. A. Izatt, "Optical coherence tomography - A new high-resolution imaging technology to study cardiac development in chick embryos," Circulation 106, 2771 (2002). [CrossRef] [PubMed]
- M. Hope-Ross, L. Yannuzzi, E. Gragoudas, D. Guyer, J. Slakter, J. Sorenson, S. Krupsky, D. Orlock, and C. A. Puliafito, "Adverse reactions due to indocyanine green," Ophthalmology 101, 5 (1994). [PubMed]
- L. Yannuzzi, K. Rohrer, L. Tindel, R. Sobel, M. Constanza, W. Shields, and E. Zang, "Fluorescein angiography complication survey," Ophthalmology 93, 7 (1986). [PubMed]
- V. Hamburger, and H. L. Hamilton, "A series of normal stages in the development of the chick embryo," J. Morphology 88, 54 (1951). [CrossRef]
Cited By |
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.
Multimedia
| Multimedia Files | Recommended Software |
| » Media 1: AVI (7726 KB) | QuickTime |
Related Journal Articles 
- Interstitial Doppler optical coherence tomography (OL)
- Phase-resolved optical frequency domain imaging (OE)
- Real-time in vivo blood-flow imaging by moving-scatterer-sensitive spectral-domain optical Doppler tomography (OL)
- Doppler optical coherence tomography with a micro-electro-mechanical membrane mirror for high-speed dynamic focus tracking (OL)
- Clutter rejection filters for optical Doppler tomography (OE)
Related Conference Papers 
- Stationary Scatterer Filtering in Spectral Domain Optical Doppler Tomography
- Quantitative Evaluation of Nanoshells as a Contrast Agent for Optical Coherence Tomography
- Bioconjugated Au/Ag Nanocages as a Novel Optical Imaging Contrast and Thermal Therapeutic Agent
- Real-Time Ultrahigh-Resolution Lateral-Priority OCT Imaging with a Broad Spectrum Throughput Acousto-Optic Modulation
- An all-digital real-time optical coherence tomographic system
- Firefox 11+
- Google Chrome 17+
- Internet Explorer 9+
- Safari 5+




OSA is a member of 