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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 11 — Oct. 22, 2008

Entangled-photon coincidence fluorescence imaging

Giuliano Scarcelli and Seok H. Yun  »View Author Affiliations

Optics Express, Vol. 16, Issue 20, pp. 16189-16194 (2008)

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We describe fluorescence imaging using the second-order correlation of entangled photon pairs. The proposed method is based on the principle that one photon of the pair carries information on where the other photon has been absorbed and has produced fluorescence in a sample. Because fluorescent molecules serve as “detectors” breaking the entanglement, multiply-scattered fluorescence photons within the sample do not cause image blur. We discuss experimental implementations.

© 2008 Optical Society of America

OCIS Codes
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(270.0270) Quantum optics : Quantum optics

ToC Category:
Quantum Optics

Original Manuscript: July 8, 2008
Revised Manuscript: August 22, 2008
Manuscript Accepted: August 29, 2008
Published: September 26, 2008

Virtual Issues
Vol. 3, Iss. 11 Virtual Journal for Biomedical Optics

Giuliano Scarcelli and Seok H. Yun, "Entangled-photon coincidence fluorescence imaging," Opt. Express 16, 16189-16194 (2008)

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  1. J. P. Dowling and G. J. Milburn, "Quantum technology: the second quantum revolution," Phil. Trans. R. Soc. London A 361, 1655-1674 (2003); [CrossRef]
  2. N. Gisin and R. Thew, "Quantum communication," Nat. Photonics 1, 165-171 (2007). [CrossRef]
  3. T. B. Pittman, Y. H. Shih, D. V. Strekalov, and A. V. Sergienko, "Optical imaging by means of two-photon quantum entanglement," Phys. Rev. A 52, R3429-R3432 (1995). [CrossRef] [PubMed]
  4. A. V. Belinskii and D. N. Klyshko, "Two-Photon Optics - Diffraction, Holography and Transformation of 2-Dimensional Signals," JETP 105, 487-493 (1994).
  5. R. S. Bennink, S. J. Bentley, and R. W. Boyd, ""Two-photon" coincidence imaging with a classical source," Phys. Rev. Lett. 89, 113601 (2002). [CrossRef] [PubMed]
  6. A. Gatti, E. Brambilla, M. Bache, and L. A. Lugiato, "Correlated imaging, quantum and classical," Phys. Rev. A 70, 013802 (2004).Q4 [CrossRef]
  7. A. Valencia, G. Scarcelli, M. D'Angelo, and Y. Shih, "Two-photon imaging with thermal light," Phys. Rev. Lett. 94, 063601 (2005). [CrossRef] [PubMed]
  8. A. F. Abouraddy, P. R. Stone, A. V. Sergienko, B. E. A. Saleh, and M. C. Teich, "Entangled-photon imaging of a pure phase object," Phys. Rev. Lett. 93, 213903 (2004). [CrossRef] [PubMed]
  9. R. J. Glauber, "Quantum theory of optical coherence," Phys. Rev. 130, 2529 (1963). [CrossRef]
  10. A. F. Abouraddy, B. E. A. Saleh, A. V. Sergienko, and M. C. Teich, "Entangled-photon Fourier optics," J. Opt. Soc. Am. B 19, 1174-1184 (2002). [CrossRef]
  11. S. Bellis, R. Wilcock, and C. Jackson, "Photon counting imaging: the digital APD," Proc. SPIE 6068, 6068D (2006).
  12. G. Scarcelli, A. Valencia, S. Gompers, and Y. Shih, "Remote spectral measurement using entangled photons," Appl. Phys. Lett. 83, 5560-5562 (2003). [CrossRef]
  13. J. T. Motz, D. Yelin, B. J. Vakoc, B. E. Bouma, and G. J. Tearney, "Spectral- and frequency-encoded fluorescence imaging," Opt. Lett. 30, 2760-2762 (2005). [CrossRef] [PubMed]
  14. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy," Science 248, 73-76 (1990). [CrossRef] [PubMed]

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