Optics InfoBase > Virtual Journal for Biomedical Optics > Volume 3 > Issue 4 > Page 4163
Improved spectral optical coherence tomography using optical frequency comb
Tomasz Bajraszewski, Maciej Wojtkowski, Maciej Szkulmowski, Anna Szkulmowska, Robert Huber, and Andrzej Kowalczyk »View Author Affiliations
1Institute of Physics, Nicolaus Copernicus University, ul. Grudziadzka 5/7, 87-100 Torun, Poland
†Fakultät für Physik, Ludwig-Maximilians-Universität München, Munich, Germany.
*Corresponding author: max@fizyka.umk.pl
Optics Express, Vol. 16, Issue 6, pp. 4163-4176 (2008)
http://dx.doi.org/10.1364/OE.16.004163
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Abstract
We identify and analyze factors influencing sensitivity drop-off in Spectral OCT and propose a system employing an Optical Frequency Comb (OFC) to verify this analysis. Spectral Optical Coherence Tomography using a method based on an optical frequency comb is demonstrated. Since the spectrum sampling function is determined by the comb rather than detector pixel distribution, this method allows to overcome limitations of high resolution Fourier-domain OCT techniques. Additionally, the presented technique also enables increased imaging range while preserving high axial resolution. High resolution cross-sectional images of biological samples obtained with the proposed technique are presented.
© 2008 Optical Society of America
OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.2230) Instrumentation, measurement, and metrology : Fabry-Perot
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(110.4155) Imaging systems : Multiframe image processing
ToC Category:
Imaging Systems
History
Original Manuscript: January 31, 2008
Revised Manuscript: March 1, 2008
Manuscript Accepted: March 7, 2008
Published: March 12, 2008
Virtual Issues
Vol. 3, Iss. 4 Virtual Journal for Biomedical Optics
Citation
Tomasz Bajraszewski, Maciej Wojtkowski, Maciej Szkulmowski, Anna Szkulmowska, Robert Huber, and Andrzej Kowalczyk, "Improved spectral optical coherence tomography using optical frequency comb," Opt. Express 16, 4163-4176 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-16-6-4163
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References
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- A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of Intraocular Distances by Backscattering Spectral Interferometry," Opt. Commun. 117, 43-48 (1995). [CrossRef]
- Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, "Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography," Appl. Opt. 45, 1861-1865 (2006). [CrossRef] [PubMed]
- T. Endo, Y. Yasuno, S. Makita, M. Itoh, and T. Yatagai, "Profilometry with line-field Fourier-domain interferometry," Opt. Express 13, 695-701 (2005). [CrossRef] [PubMed]
- U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, "Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases," Investigative ophthalmology & visual science 46, 3393-3402 (2005). [CrossRef] [PubMed]
- R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of Fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003). [CrossRef] [PubMed]
- M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed.Opt. 7, 457-463 (2002). [CrossRef] [PubMed]
- M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, "Full range complex spectral optical coherence tomography technique in eye imaging," Opt. Lett. 27, 1415-1417 (2002). [CrossRef]
- F. Lexer, C. K. Hitzenberger, A. F. Fercher, and M. Kulhavy, "Wavelength-tuning interferometry of intraocular distances," Appl. Opt. 36, 6548-6553 (1997). [CrossRef]
- A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of Intraocular Distances by Backscattering Spectral Interferometry," Opt. Commun. 117, 43-48 (1995). [CrossRef]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- V. Christopoulos, L. Kagemann, G. Wollstein, H. Ishikawa, M. L. Gabriele, M. Wojtkowski, V. Srinivasan, J. G. Fujimoto, J. S. Duker, D. K. Dhaliwal, and J. S. Schuman, "In vivo corneal high-speed, ultra high-resolution optical coherence tomography," Archives of ophthalmology 125, 1027-1035 (2007). [CrossRef] [PubMed]
- V. J. Srinivasan, R. Huber, I. Gorczynska, J. G. Fujimoto, J. Y. Jiang, P. Reisen, and A. E. Cable, "High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm," Opt. Lett. 32, 361-363 (2007). [CrossRef] [PubMed]
- D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, "Three-dimensional endomicroscopy using optical coherence tomography," Nature Photonics 1, 709-716 (2007). [CrossRef]
- R. Huber, D. C. Adler, and J. G. Fujimoto, "Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s," Opt. Lett. 31, 2975-2977 (2006). [CrossRef] [PubMed]
- V. J. Srinivasan, M. Wojtkowski, A. J. Witkin, J. S. Duker, T. H. Ko, M. Carvalho, J. S. Schuman, A. Kowalczyk, and J. G. Fujimoto, "High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 113, 2054 e2051-2014 (2006). [CrossRef] [PubMed]
- M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12, 2404-2422 (2004). [CrossRef] [PubMed]
- S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22, 340-342 (1997). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
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- S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Pulsed-source and swept-source spectral-domain optical coherence tomography with reduced motion artifacts," Opt. Express 12, 5614-5624 (2004). [CrossRef] [PubMed]
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Am. J. Ophthalmol.
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Appl. Opt.
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Archives of ophthalmology
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European journal of ophthalmology
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Investigative ophthalmology & visual science
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J. Biomed.Opt.
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Nature Photonics
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Ophthalmology
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Opt. Commun.
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Opt. Express
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Opt. Lett.
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Science
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2007, Kaluzny, European journal of ophthalmology
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