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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 8 — Jul. 30, 2009

Three-dimensional quantitative imaging of retinal and choroidal blood flow velocity using joint Spectral and Time domain Optical Coherence Tomography

Anna Szkulmowska, Maciej Szkulmowski, Daniel Szlag, Andrzej Kowalczyk, and Maciej Wojtkowski  »View Author Affiliations


Optics Express, Vol. 17, Issue 13, pp. 10584-10598 (2009)
http://dx.doi.org/10.1364/OE.17.010584


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Abstract

Recently, joint Spectral and Time domain Optical Coherence Tomography (joint STdOCT) has been proposed to measure ocular blood flow velocity. Limitations of CCD technology allowed only for two-dimensional imaging at that time. In this paper we demonstrate fast three-dimensional STdOCT based on ultrahigh speed CMOS camera. Proposed method is straightforward, fully automatic and does not require any advanced image processing techniques. Three-dimensional distributions of axial velocity components of the blood in human eye vasculature are presented: in retinal and, for the first time, in choroidal layer. Different factors that affect quality of velocity images are discussed. Additionally, the quantitative measurement allows to observe a new interesting optical phenomenon – random Doppler shift in OCT signals that forms a vascular pattern at the depth of sclera.

© 2009 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 10, 2009
Revised Manuscript: May 22, 2009
Manuscript Accepted: June 5, 2009
Published: June 9, 2009

Virtual Issues
Vol. 4, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Anna Szkulmowska, Maciej Szkulmowski, Daniel Szlag, Andrzej Kowalczyk, and Maciej Wojtkowski, "Three-dimensional quantitative imaging
of retinal and choroidal blood flow velocity using joint Spectral and Time domain Optical Coherence Tomography," Opt. Express 17, 10584-10598 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-13-10584


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References

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