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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 9 — Sep. 4, 2009

Single-shot two-dimensional full-range optical coherence tomography achieved by dispersion control

S. Witte, M. Baclayon, E. J. G. Peterman, R. F. G. Toonen, H. D. Mansvelder, and M. L. Groot  »View Author Affiliations


Optics Express, Vol. 17, Issue 14, pp. 11335-11349 (2009)
http://dx.doi.org/10.1364/OE.17.011335


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Abstract

We present a full-range Fourier-domain optical coherence tomography (OCT) system that is capable of acquiring two-dimensional images of living tissue in a single shot. By using line illumination of the sample in combination with a two-dimensional imaging spectrometer, 1040 depth scans are performed simultaneously on a sub-millisecond timescale. Furthermore, we demonstrate an easy and flexible real-time single-shot technique for full-range (complex-conjugate cancelled) OCT imaging that is compatible with both two-dimensional as well as ultrahigh-resolution OCT. By implementing a dispersion imbalance between reference and sample arms of the interferometer, we eliminate the complex-conjugate signal through numerical dispersion compensation, effectively increasing the useful depth range by a factor of two. The system allows us to record 6.7×3.2 mm images at 5 µm depth resolution in 0.2 ms. Data postprocessing requires only 4 s. We demonstrate the capability of our system by imaging the anterior chamber of a mouse eye in vitro, as well as human skin in vivo.

© 2009 Optical Society of America

OCIS Codes
(070.0070) Fourier optics and signal processing : Fourier optics and signal processing
(100.5070) Image processing : Phase retrieval
(110.0110) Imaging systems : Imaging systems
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(320.1590) Ultrafast optics : Chirping
(110.3010) Imaging systems : Image reconstruction techniques

ToC Category:
Imaging Systems

History
Original Manuscript: April 17, 2009
Revised Manuscript: May 27, 2009
Manuscript Accepted: June 2, 2009
Published: June 22, 2009

Virtual Issues
Vol. 4, Iss. 9 Virtual Journal for Biomedical Optics

Citation
S. Witte, M. Baclayon, E. J. Peterman, R. F. Toonen, H. D. Mansvelder, and M. L. Groot, "Single-shot two-dimensional full-range optical coherence tomography achieved by dispersion control," Opt. Express 17, 11335-11349 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-14-11335


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