OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 10 — Oct. 2, 2009

Investigation of inclined dual-fiber optical tweezers for 3D manipulation and force sensing

Yuxiang Liu and Miao Yu  »View Author Affiliations

Optics Express, Vol. 17, Issue 16, pp. 13624-13638 (2009)

View Full Text Article

Enhanced HTML    Acrobat PDF (819 KB) Open Access

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Optical tweezers provide a versatile tool in biological and physical researches. Optical tweezers based on optical fibers are more flexible and ready to be integrated when compared with those based on microscope objectives. In this paper, the three-dimensional (3D) trapping ability of an inclined dual-fiber optical tweezers is demonstrated. The trapping efficiency with respect to displacement is experimentally calibrated along two dimensions. The system is studied numerically using a modified ray-optics model. The spring constants obtained in the experiment are predicted by simulations. It is found both experimentally and numerically that there is a critical value for the fiber inclination angle to retain the 3D trapping ability. The inclined dual-fiber optical tweezers are demonstrated to be more robust to z-axis misalignment than the counter-propagating fiber optical tweezers, which is a special case of the former when the fiber inclination angle is 90°. This inclined dual-fiber optical tweezers can serve as both a manipulator and a force sensor in integrated systems, such as microfluidic systems and lab-on-a-chip systems.

© 2009 Optical Society of America

OCIS Codes
(060.2310) Fiber optics and optical communications : Fiber optics
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Optical Trapping and Manipulation

Original Manuscript: June 10, 2009
Revised Manuscript: July 10, 2009
Manuscript Accepted: July 11, 2009
Published: July 23, 2009

Virtual Issues
Vol. 4, Iss. 10 Virtual Journal for Biomedical Optics

Yuxiang Liu and Miao Yu, "Investigation of inclined dual-fiber optical tweezers for 3D manipulation and force sensing," Opt. Express 17, 13624-13638 (2009)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. K. C. Neuman and S. M. Block, "Optical trapping," Rev. Sci. Instrum. 75, 2787 (2004). [CrossRef]
  2. A. Ashkin, "History of optical trapping and manipulation of small-neutral particle, atoms, and molecules," IEEE J. Sel. Top. Quantum Electron. 6, 841 (2000). [CrossRef]
  3. D. G. Grier, "Optical tweezers in colloid and interface science," Curr. Opin. Colloid. In. 2, 264 (1997). [CrossRef]
  4. S. Hormeno and J. R. Arias-Gonzalez, "Exploring mechanochemical processes in the cell with optical tweezers," Biol. Cell 98, 679 (2006). [CrossRef] [PubMed]
  5. E. A. Abbondanzieri, W. J. Greenleaf, J. W. Shaevitz, R. Landick and S. M. Block, "Direct observation of base-pair stepping by RNA polymerase," Nature 438, 460 (2005). [CrossRef] [PubMed]
  6. Z. Hu, J. Wang and J. Liang, "Theoretical and experimental investigation of the optical trapping force in single lensed fibre trapping," J. Opt. A-Pure Appl. Opt.  8, 891 (2006). [CrossRef]
  7. K. Taguchi, H. Ueno, T. Hiramatsu and M. Ikeda, "Optical trapping of dielectric particle and biological cell using optical fibre," Electron. Lett. 33, 413 (1997). [CrossRef]
  8. K. S. Abedin, C. Kerbage, A. Fernandez-Nieves and D. A. Weitz, "Optical manipulation and rotation of liquid crystal drops using high-index fiber-optics tweezers," Appl. Phys. Lett. 91, 091119 (2007). [CrossRef]
  9. T. Numata, A. Takayanagi, Y. Otani and N. Umeda, "Manipulation of metal nanoparticles using fiber-optic laser tweezers with a microspherical focusing lens," Jpn. J. Appl. Phys. 45, 359 (2006). [CrossRef]
  10. R. S. Taylor and C. Hnatovsky, "Particle trapping in 3-D using a single fiber probe with an annular light distribution," Opt. Express,  11, 2775 (2003), http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-11-21-2775. [CrossRef] [PubMed]
  11. Z. Liu, C. Guo, J. Yang and L. Yuan, "Tapered fiber optical tweezers for microscopic particle trapping: fabrication and application," Opt. Express 14,12510 (2006), http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-14-25-12510. [CrossRef] [PubMed]
  12. L. Yuan, Z. Liu, J. Yang, and C. Guan, "Twin-core fiber optical tweezers," Opt. Express 16, 4551 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-16-7-4559. [CrossRef]
  13. C. Liberale, P. Minzioni, F. Bragheri, F. De Angelis, E. Di Fabrizio, and I Cristiani, "Miniaturized all-fiber probe for three-dimensional optical trapping and manipulation," Nat. Photonics 1, 723 (2007). [CrossRef]
  14. F. Bragheri, P. Minzioni, C. Liberale, E. Di Fabrizio, and I. Cristiani, "Design and optimization of a reflection-based fiber-optic tweezers," Opt. Express 16, 17647 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-16-22-17647. [CrossRef] [PubMed]
  15. M. Wei, K. Yang, A. Karmenyan, and A. Chiou, "Three-dimensional optical force field on a Chinese hamster ovary cell in a fiber-optical dual-beam trap," Opt. Express 14, 3056 (2006), http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-14-7-3056. [CrossRef] [PubMed]
  16. E. Sidick, S. D. Collins, and A. Knoesen, "Trapping forces in a multiple-beam fiber-optic trap," Appl. Optics 36, 6423 (1997). [CrossRef]
  17. A. Constable, J. Kim, J. Mervis, F. Zarinetchi and M. Prentiss, "Demonstration of a fiber-optical light-force trap," Opt. Lett. 18, 1867 (1993). [CrossRef] [PubMed]
  18. E. R. Lyons and G. J. Sonek, "Confinement and bistability in a tapered hemispheically lensed optical fiber trap," Appl. Phys. Lett. 66, 1584 (1995). [CrossRef]
  19. J. Guck, R. Ananthakrishnan, H. Mahmood, T. J. Moon, C. C. Cunningham, J. Kas, "The optical stretcher: a novel laser tool to micromanipulate cells," Biophys. J. 81, 767 (2001). [CrossRef] [PubMed]
  20. K. Taguchi, K. Atsuta, T. Nakata and M. Ideda, "Levitation of a microscopic object using plural optical fibers," Opt. Commun. 176, 43 (2000). [CrossRef]
  21. K. Taguchi, M. Tanaka and M. Ikeda, "Dual-beam trapping method for an object with large relative refractive index," Jpn. J. Appl. Phys. 39, L1302 (2000). [CrossRef]
  22. K. Taguchi, M. Tanaka and M. Ikeda, "Investigation on the radius of a hemispherical microlens of an optical fiber end for three-dimensional trapping," Opt. Quantum Electron. 34, 993 (2002). [CrossRef]
  23. S. Vogel, Life in Moving Fluids: The physical Biology of Flow, Second Edition, Revised and Expanded (Princeton University Press, 1994), Chap. 15.
  24. A. Ashkin, "Forces of a single-beam gradient laser trap on a dielectric sphere in the ray optics regime," Biophys. J. 61, 569 (1992). [CrossRef] [PubMed]
  25. H. Lamb, Hydrodynamics, Sixth Edition (Dover Publications, 1945), Chapter XI, Page 616.
  26. F. Cardarelli, Materials Handbook, A Concise Desktip Reference, Second Edition (Springer, 2008), Chap. 10, pp. 672-675.
  27. K. Berg-Sørensen and H. Flyvbjerg, "Power spectrum analysis for optical tweezers," Rev. Sci. Instrum. 75, 594 (2004). [CrossRef]
  28. R. C. Gauthier, "Optical trapping: a tool to assist optical machining," Opt. Laser Technol. 29, 389 (1997). [CrossRef]
  29. Y. Liu and M. Yu, "Three-dimensional fiber optical trap for cell manipulation and force measurement," Proc. SPIE 6528, 65280Z (2007). [CrossRef]
  30. A. Priyadarshi, L. H. Fen, S. G. Mhaisalkar, V. Kripesh, and A. K. Asundi, "Fiber misalignment in silicon V-groove based optical modules," Opt. Fiber Technol. 12, 170 (2006). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Supplementary Material

» Media 1: MOV (2664 KB)     

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited