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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 11 — Oct. 21, 2009

Silicon-on-insulator guided mode resonant grating for evanescent field molecular sensing

J. H. Schmid, W. Sinclair, J. García, S. Janz, J. Lapointe, D. Poitras, Y. Li, T. Mischki, G. Lopinski, P. Cheben, A. Delâge, A. Densmore, P. Waldron, and D.-X. Xu  »View Author Affiliations


Optics Express, Vol. 17, Issue 20, pp. 18371-18380 (2009)
http://dx.doi.org/10.1364/OE.17.018371


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Abstract

We present experimental and theoretical results of label-free molecular sensing using the transverse magnetic mode of a 0.22 μm thick silicon slab waveguide with a surface grating implemented in a guided mode resonance configuration. Due to the strong overlap of the evanescent field of the waveguide mode with a molecular layer attached to the surface, these sensors exhibit high sensitivity, while their fabrication and packaging requirements are modest. Experimentally, we demonstrate a resonance wavelength shift of ~1 nm when a monolayer of the protein streptavidin is attached to the surface, in good agreement with calculations based on rigorous coupled wave analysis. In our current optical setup this shift corresponds to an estimated limit of detection of 0.2% of a monolayer of streptavidin.

© 2009 OSA

OCIS Codes
(050.2770) Diffraction and gratings : Gratings
(130.3120) Integrated optics : Integrated optics devices
(130.6010) Integrated optics : Sensors
(230.5750) Optical devices : Resonators

ToC Category:
Integrated Optics

History
Original Manuscript: August 19, 2009
Revised Manuscript: September 20, 2009
Manuscript Accepted: September 20, 2009
Published: September 25, 2009

Virtual Issues
Vol. 4, Iss. 11 Virtual Journal for Biomedical Optics

Citation
J. H. Schmid, W. Sinclair, J. García, S. Janz, J. Lapointe, D. Poitras, Y. Li, T. Mischki, G. Lopinski, P. Cheben, A. Delâge, A. Densmore, P. Waldron, and D.-X. Xu, "Silicon-on-insulator guided mode resonant grating for evanescent field molecular sensing," Opt. Express 17, 18371-18380 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-20-18371


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References

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