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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 12 — Nov. 10, 2009

3D shape based reconstruction of experimental data in Diffuse Optical Tomography

Athanasios Zacharopoulos, Martin Schweiger, Ville Kolehmainen, and Simon Arridge  »View Author Affiliations


Optics Express, Vol. 17, Issue 21, pp. 18940-18956 (2009)
http://dx.doi.org/10.1364/OE.17.018940


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Abstract

Diffuse optical tomography (DOT) aims at recovering three-dimensional images of absorption and scattering parameters inside diffusive body based on small number of transmission measurements at the boundary of the body. This image reconstruction problem is known to be an ill-posed inverse problem, which requires use of prior information for successful reconstruction. We present a shape based method for DOT, where we assume a priori that the unknown body consist of disjoint subdomains with different optical properties. We utilize spherical harmonics expansion to parameterize the reconstruction problem with respect to the subdomain boundaries, and introduce a finite element (FEM) based algorithm that uses a novel 3D mesh subdivision technique to describe the mapping from spherical harmonics coefficients to the 3D absorption and scattering distributions inside a unstructured volumetric FEM mesh. We evaluate the shape based method by reconstructing experimental DOT data, from a cylindrical phantom with one inclusion with high absorption and one with high scattering. The reconstruction was monitored, and we found a 87% reduction in the Hausdorff measure between targets and reconstructed inclusions, 96% success in recovering the location of the centers of the inclusions and 87% success in average in the recovery for the volumes.

© 2009 Optical Society of America

OCIS Codes
(100.3190) Image processing : Inverse problems
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Image Processing

History
Original Manuscript: July 21, 2009
Revised Manuscript: September 16, 2009
Manuscript Accepted: September 28, 2009
Published: October 8, 2009

Virtual Issues
Vol. 4, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Athanasios D. Zacharopoulos, Martin Schweiger, Ville Kolehmainen, and Simon Arridge, "3D shape based reconstruction of experimental data in Diffuse Optical Tomography," Opt. Express 17, 18940-18956 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-21-18940


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