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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 4 — Apr. 1, 2009

Designing efficient zero calibration point for phase-sensitive surface plasmon resonance biosensing

S. Patskovsky, M. Vallieres, M. Maisonneuve, In-Hyouk Song, M. Meunier, and A. V. Kabashin  »View Author Affiliations


Optics Express, Vol. 17, Issue 4, pp. 2255-2263 (2009)
http://dx.doi.org/10.1364/OE.17.002255


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Abstract

This work is related to the development of phase-sensitive methodologies in Surface Plasmon Resonance (SPR) biosensing. We take advantage of a specific angular dependence of phase of light, reflected under SPR geometry, on parameters of the SPR-supporting metal, and propose a polarimetry-based methodology to easily determine the optimal calibration zero point, corresponding to the maximal phase sensitivity. The proposed methodology can significantly facilitate the calibration of the system in field and multi-channel sensing, broaden the dynamic range, as well as contribute to the development of feedback loops.

© 2009 Optical Society of America

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Optics at Surfaces

History
Original Manuscript: November 30, 2008
Revised Manuscript: January 23, 2009
Manuscript Accepted: January 23, 2009
Published: February 4, 2009

Virtual Issues
Vol. 4, Iss. 4 Virtual Journal for Biomedical Optics

Citation
S. Patskovsky, M. Vallieres, M. Maisonneuve, In-Hyouk Song, M. Meunier, and A. V. Kabashin, "Designing efficient zero calibration point for phase-sensitive surface plasmon resonance biosensing," Opt. Express 17, 2255-2263 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-4-2255


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