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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 4 — Apr. 1, 2009

Polymer photonic crystal dye lasers as Optofluidic Cell Sensors

Mads Brøkner Christiansen, Joanna Malgorzata Lopacinska, Mogens Havsteen Jakobsen, Niels Asger Mortensen, Martin Dufva, and Anders Kristensen  »View Author Affiliations


Optics Express, Vol. 17, Issue 4, pp. 2722-2730 (2009)
http://dx.doi.org/10.1364/OE.17.002722


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Abstract

Dye doped hybrid polymer lasers are implemented as label free evanescent field biosensors for detection of cells. It is demonstrated that although the coverage is irregular and the cells extend over several lattice constants, the emission wavelength depends linearly on the fraction of the surface covered by the HeLa cells used as model system. Design parameters relating to photonic crystal sensing of large objects are identified and discussed. The lasers are chemically modified to bind cells and molecules with flexible UV activated linker molecules.

© 2009 Optical Society of America

OCIS Codes
(140.2050) Lasers and laser optics : Dye lasers
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(050.5298) Diffraction and gratings : Photonic crystals

ToC Category:
Lasers and Laser Optics

History
Original Manuscript: January 13, 2009
Revised Manuscript: February 7, 2009
Manuscript Accepted: February 7, 2009
Published: February 10, 2009

Virtual Issues
Vol. 4, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Mads Brokner Christiansen, Joanna Malgorzata Lopacinska, Mogens Havsteen Jakobsen, Niels Asger Mortensen, Martin Dufva, and Anders Kristensen, "Polymer photonic crystal dye lasers as Optofluidic Cell Sensors," Opt. Express 17, 2722-2730 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-4-2722


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