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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 5 — May. 5, 2009

Analysis and experimental assessment of the sensitivity of stimulated Raman scattering microscopy

Yasuyuki Ozeki, Fumihiro Dake, Shin’ichiro Kajiyama, Kiichi Fukui, and Kazuyoshi Itoh  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 3651-3658 (2009)
http://dx.doi.org/10.1364/OE.17.003651


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Abstract

We theoretically show that the shot-noise-limited sensitivity of stimulated Raman scattering (SRS) microscopy, which enables high-contrast vibrational imaging, is similar to that of coherent anti-Stokes Raman scattering microscopy. We experimentally confirm that the sensitivity of our SRS microscope is lower than the shot-noise limit only by <15 dB, which indicates that the high-sensitivity of SRS microscopy is readily available.

© 2009 Optical Society of America

OCIS Codes
(180.6900) Microscopy : Three-dimensional microscopy
(190.2640) Nonlinear optics : Stimulated scattering, modulation, etc.
(190.4410) Nonlinear optics : Nonlinear optics, parametric processes
(300.6290) Spectroscopy : Spectroscopy, four-wave mixing
(180.5655) Microscopy : Raman microscopy

ToC Category:
Microscopy

History
Original Manuscript: January 16, 2009
Revised Manuscript: February 21, 2009
Manuscript Accepted: February 21, 2009
Published: February 24, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Yasuyuki Ozeki, Fumihiro Dake, Shin'ichiro Kajiyama, Kiichi Fukui, and Kazuyoshi Itoh, "Analysis and experimental assessment of the sensitivity of stimulated Raman scattering microscopy," Opt. Express 17, 3651-3658 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-5-3651


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References

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