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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 5 — May. 5, 2009

Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography

Maciej Wojtkowski, Bartosz L. Sikorski, Iwona Gorczynska, Michalina Gora, Maciej Szkulmowski, Danuta Bukowska, Jakub Kałuzny, James G. Fujimoto, and Andrzej Kowalczyk  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 4189-4207 (2009)
http://dx.doi.org/10.1364/OE.17.004189


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Abstract

We demonstrate and compare two image processing methods for visualization and analysis of three-dimensional optical coherence tomography (OCT) data acquired in eyes with different retinal pathologies. A method of retinal layer segmentation based on a multiple intensity thresholding algorithm was implemented in order to generate simultaneously outer retinal topography maps and reflectivity maps. We compare the applicability of the two methods to the diagnosis of retinal diseases and their progression. The data presented in this contribution were acquired with a high speed (25,000 A-scans/s), high resolution (4.5 µm) spectral OCT prototype instrument operating in the ophthalmology clinic.

© 2009 Optical Society of America

OCIS Codes
(100.2000) Image processing : Digital image processing
(170.1610) Medical optics and biotechnology : Clinical applications
(170.1650) Medical optics and biotechnology : Coherence imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Visualization and Image Processing in OCT

History
Original Manuscript: July 28, 2008
Revised Manuscript: January 21, 2009
Manuscript Accepted: January 23, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Maciej Wojtkowski, Bartosz L. Sikorski, Iwona Gorczynska, Michalina Gora, Maciej Szkulmowski, Danuta Bukowska, Jakub Kaluzny, James G. Fujimoto, and Andrzej Kowalczyk, "Comparison of reflectivity maps and outer retinal topography in retinal disease by 3-D Fourier domain optical coherence tomography," Opt. Express 17, 4189-4207 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-5-4189


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