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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 11 — Aug. 25, 2010

Multiple-channel spectrally encoded imaging

Avraham Abramov, Limor Minai, and Dvir Yelin  »View Author Affiliations


Optics Express, Vol. 18, Issue 14, pp. 14745-14751 (2010)
http://dx.doi.org/10.1364/OE.18.014745


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Abstract

Spectrally encoded endoscopy (SEE) uses miniature diffractive optics to encode space with wavelength, allowing video-rate three-dimensional imaging through sub-millimeter, flexible endoscopic probes. Here we present a new approach for SEE in which the illumination and the collection channels are separated in space, and spectral encoding is present only in the collection channel. Bench-top experiments using spatially incoherent white light illumination reveal significant improvement in image quality and considerable reduction of speckle noise compared to conventional techniques, and show that the new system is capable of high sensitivity fluorescence imaging of single cells. The presented new approach would allow improved functionality and usability of SEE.

© 2010 OSA

OCIS Codes
(050.1970) Diffraction and gratings : Diffractive optics
(110.2350) Imaging systems : Fiber optics imaging
(170.0110) Medical optics and biotechnology : Imaging systems
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(260.2510) Physical optics : Fluorescence
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 8, 2010
Revised Manuscript: April 11, 2010
Manuscript Accepted: April 12, 2010
Published: June 25, 2010

Virtual Issues
Vol. 5, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Avraham Abramov, Limor Minai, and Dvir Yelin, "Multiple-channel spectrally encoded imaging," Opt. Express 18, 14745-14751 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-14-14745


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