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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 12 — Sep. 30, 2010

Fast noncontact measurements of tablet dye concentration

Ervin Nippolainen, Tuomas Ervasti, Laure Fauch, Serguei V. Miridonov, Jarkko Ketolainen, and Alexei A. Kamshilin  »View Author Affiliations


Optics Express, Vol. 18, Issue 15, pp. 15624-15634 (2010)
http://dx.doi.org/10.1364/OE.18.015624


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Abstract

A non-contact, non-destructive technique for estimating the dye concentration of a tablet is presented. These measurements are performed by an optoelectronic system capable for fast acquisition of two-dimensional distribution of reflection spectra with high spatial resolution by using a subspace vector model of surface reflection. Vector components representing compressed spectral data are used directly (without reconstruction of the reflection spectra) for discrimination of tablets with small dye-concentration difference. Analysis of the data obtained after tablet illumination by 7 mutually orthogonal spectral functions allows us to find a single optimal spectral function which is enough for estimating the dye concentration. Using the optimal spectral function, either the mean concentration of riboflavin or distribution of the concentration over the tablet surface can be evaluated with high rate which ensures application of the technique for online quality control of each tablet.

© 2010 OSA

OCIS Codes
(100.5010) Image processing : Pattern recognition
(330.0330) Vision, color, and visual optics : Vision, color, and visual optics
(330.6180) Vision, color, and visual optics : Spectral discrimination
(110.4234) Imaging systems : Multispectral and hyperspectral imaging

ToC Category:
Vision, Color, and Visual Optics

History
Original Manuscript: May 13, 2010
Revised Manuscript: June 11, 2010
Manuscript Accepted: June 14, 2010
Published: July 8, 2010

Virtual Issues
Vol. 5, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Ervin Nippolainen, Tuomas Ervasti, Laure Fauch, Serguei V. Miridonov, Jarkko Ketolainen, and Alexei A. Kamshilin, "Fast noncontact measurements of tablet dye concentration," Opt. Express 18, 15624-15634 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-15-15624


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