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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 12 — Sep. 30, 2010

X-ray phase contrast microscopy at 300 nm resolution with laboratory sources

Daniele Pelliccia, Andrea Sorrentino, Inna Bukreeva, Alessia Cedola, Fernando Scarinci, Mihaela Ilie, Anna Maria Gerardino, Michela Fratini, and Stefano Lagomarsino  »View Author Affiliations

Optics Express, Vol. 18, Issue 15, pp. 15998-16004 (2010)

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We report the performance of an X-ray phase contrast microscope for laboratory sources with 300 nm spatial resolution. The microscope is based on a commercial X-ray microfocus source equipped with a planar X-ray waveguide able to produce a sub-micrometer x-ray beam in one dimension. Phase contrast images of representative samples are reported. The achieved contrast and resolution is discussed for different configurations. The proposed approach could represent a simple, inexpensive, solution for sub-micrometer resolution imaging with small laboratory setups.

© 2010 OSA

OCIS Codes
(340.0340) X-ray optics : X-ray optics
(340.7440) X-ray optics : X-ray imaging
(340.7460) X-ray optics : X-ray microscopy

ToC Category:
X-ray Optics

Original Manuscript: March 15, 2010
Revised Manuscript: April 19, 2010
Manuscript Accepted: May 9, 2010
Published: July 14, 2010

Virtual Issues
Vol. 5, Iss. 12 Virtual Journal for Biomedical Optics

Daniele Pelliccia, Andrea Sorrentino, Inna Bukreeva, Alessia Cedola, Fernando Scarinci, Mihaela Ilie, Anna Maria Gerardino, Michela Fratini, and Stefano Lagomarsino, "X-ray phase contrast microscopy at 300 nm resolution with laboratory sources," Opt. Express 18, 15998-16004 (2010)

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