OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 1 — Jan. 3, 2011

Polarization-sensitive spectral-domain optical coherence tomography using a multi-line single camera spectrometer

Cheol Song, MyoungKi Ahn, and DaeGab Gweon  »View Author Affiliations


Optics Express, Vol. 18, Issue 23, pp. 23805-23817 (2010)
http://dx.doi.org/10.1364/OE.18.023805


View Full Text Article

Enhanced HTML    Acrobat PDF (1508 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We describe a polarization sensitive spectral domain optical coherence tomography technique based on a single camera spectrometer that includes a multiplexed custom grating, camera lenses, and a high-speed three-line CCD camera. Two orthogonally polarized beams could be separately taken by two lines of the camera as a result of vertically different incident angles. The system could provide the imaging capabilities of a full camera speed and increased measurable depth. The proposed optical coherence tomography system could make a distinction between the normal muscle and cancerous tissue from the chest of a DSred GFP mouse and the OCT images were compared with those of in vivo confocal microscopy.

© 2010 OSA

OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(230.5440) Optical devices : Polarization-selective devices

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 29, 2010
Revised Manuscript: October 17, 2010
Manuscript Accepted: October 22, 2010
Published: October 27, 2010

Virtual Issues
Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Cheol Song, MyoungKi Ahn, and DaeGab Gweon, "Polarization-sensitive spectral-domain optical coherence tomography using a multi-line single camera spectrometer," Opt. Express 18, 23805-23817 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-23-23805


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991). [CrossRef] [PubMed]
  2. G. Häusler and M. W. Lindner, “Coherence radar and spectral radar - new tools for dermatological diagnosis,” J. Biomed. Opt. 3(1), 21–31 (1998). [CrossRef]
  3. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, “Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,” Opt. Lett. 28(21), 2067–2069 (2003). [CrossRef] [PubMed]
  4. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, “Performance of fourier domain vs. time domain optical coherence tomography,” Opt. Express 11(8), 889–894 (2003). [CrossRef] [PubMed]
  5. J. F. de Boer, T. E. Milner, M. J. C. van Gemert, and J. S. Nelson, “Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography,” Opt. Lett. 22(12), 934–936 (1997). [CrossRef] [PubMed]
  6. J. F. De Boer, S. M. Srinivas, A. Malekafzali, Z. Chen, and J. S. Nelson, “Imaging thermally damaged by polarization-sensitive optical coherence tomography,” Opt. Express 3(6), 212–218 (1998). [CrossRef] [PubMed]
  7. M. J. Everett, K. Schoenenberger, B. W. Colston, and L. B. Da Silva, “Birefringence characterization of biological tissue by use of optical coherence tomography,” Opt. Lett. 23(3), 228–230 (1998). [CrossRef]
  8. J. F. de Boer, S. M. Srinivas, B. H. Park, T. H. Pham, Z. Chen, T. E. Milner, and J. S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5(4), 1200–1204 (1999). [CrossRef]
  9. M. G. Ducros, J. F. de Boer, H.-E. Huang, L. C. Chao, Z. Chen, J. S. Nelson, T. E. Milner, and H. G. Rylander, “Polarization sensitive optical coherence tomography of the rabbit eye,” IEEE J. Sel. Top. Quantum Electron. 5(4), 1159–1167 (1999). [CrossRef]
  10. S. Yazdanfar, M. D. Kulkarni, and J. A. Izatt, “High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography,” Opt. Express 1(13), 424–431 (1997). [CrossRef] [PubMed]
  11. Z. Chen, Y. Zhao, S. M. Srinivas, J. S. Nelson, N. Prakash, and R. D. Frostig, “Optical Doppler tomography,” IEEE J. Sel. Top. Quantum Electron. 5(4), 1134–1142 (1999). [CrossRef]
  12. Y. Wang, A. Fawzi, O. Tan, J. Gil-Flamer, and D. Huang, “Retinal blood flow detection in diabetic patients by Doppler Fourier domain optical coherence tomography,” Opt. Express 17(5), 4061–4073 (2009). [CrossRef] [PubMed]
  13. U. Morgner, W. Drexler, F. X. Kärtner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, “Spectroscopic optical coherence tomography,” Opt. Lett. 25(2), 111–113 (2000). [CrossRef]
  14. C. Xu, C. Vinegoni, T. S. Ralston, W. Luo, W. Tan, and S. A. Boppart, “Spectroscopic spectral-domain optical coherence microscopy,” Opt. Lett. 31(8), 1079–1081 (2006). [CrossRef] [PubMed]
  15. F. Robles, R. N. Graf, and A. Wax, “Dual window method for processing spectroscopic optical coherence tomography signals with simultaneously high spectral and temporal resolution,” Opt. Express 17(8), 6799–6812 (2009). [CrossRef] [PubMed]
  16. J. Yi, J. Gong, and X. Li, “Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography,” Opt. Express 17(15), 13157–13167 (2009). [CrossRef] [PubMed]
  17. M. R. Hee, D. Huang, E. A. Swanson, and J. G. Fujimoto, “Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging,” J. Opt. Soc. Am. B 9(6), 903–908 (1992). [CrossRef]
  18. Y. Yasuno, S. Makita, Y. Sutoh, M. Itoh, and T. Yatagai, “Birefringence imaging of human skin by polarization-sensitive spectral interferometric optical coherence tomography,” Opt. Lett. 27(20), 1803–1805 (2002). [CrossRef]
  19. E. Götzinger, M. Pircher, and C. K. Hitzenberger, “High speed spectral domain polarization sensitive optical coherence tomography of the human retina,” Opt. Express 13(25), 10217–10229 (2005). [CrossRef] [PubMed]
  20. B. Baumann, E. Götzinger, M. Pircher, and C. K. Hitzenberger, “Single camera based spectral domain polarization sensitive optical coherence tomography,” Opt. Express 15(3), 1054–1063 (2007). [CrossRef] [PubMed]
  21. B. Cense, M. Mujat, T. C. Chen, B. H. Park, and J. F. de Boer, “Polarization-sensitive spectral-domain optical coherence tomography using a single line scan camera,” Opt. Express 15(5), 2421–2431 (2007). [CrossRef] [PubMed]
  22. M. Zhao and J. A. Izatt, “Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging,” Opt. Lett. 34(2), 205–207 (2009). [CrossRef] [PubMed]
  23. S.-W. Lee, H.-W. Jeong, and B.-M. Kim, “High-speed spectral domain polarization-sensitive optical coherence tomography using a single camera and an optical switch at 1.3 µm,” J. Biomed. Opt. 15(1), 010501 (2010). [CrossRef] [PubMed]
  24. C. Fan, Y. Wang, and R. K. Wang, “Spectral domain polarization sensitive optical coherence tomography achieved by single camera detection,” Opt. Express 15(13), 7950–7961 (2007). [CrossRef] [PubMed]
  25. T. Schmoll, E. Götzinger, M. Pircher, C. K. Hitzenberger, and R. A. Leitgeb, “Single-camera polarization-sensitive spectral-domain OCT by spatial frequency encoding,” Opt. Lett. 35(2), 241–243 (2010). [CrossRef] [PubMed]
  26. N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, “In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography,” Opt. Lett. 29(5), 480–482 (2004). [CrossRef] [PubMed]
  27. K. Schoenenberger, B. W. Colston, D. J. Maitland, L. B. Da Silva, and M. J. Everett, “Mapping of birefringence and thermal damage in tissue by use of polarization-sensitive optical coherence tomography,” Appl. Opt. 37(25), 6026–6036 (1998). [CrossRef]
  28. C. K. Hitzenberger, E. Goetzinger, M. Sticker, M. Pircher, and A. F. Fercher, “Measurement and imaging of birefringence and optic axis orientation by phase resolved polarization sensitive optical coherence tomography,” Opt. Express 9(13), 780–790 (2001). [CrossRef] [PubMed]
  29. M. Mujat, B. H. Park, B. Cense, T. C. Chen, and J. F. de Boer, “Autocalibration of spectral-domain optical coherence tomography spectrometers for in vivo quantitative retinal nerve fiber layer birefringence determination,” J. Biomed. Opt. 12(4), 041205 (2007). [CrossRef] [PubMed]
  30. A. B. Shafer, L. R. Megill, and L. Droppleman, “Optimization of the Czerny-Turner spectrometer,” J. Opt. Soc. Am. 54(7), 879–887 (1964). [CrossRef]
  31. D. R. Austin, T. Witting, and I. A. Walmsley, “Broadband astigmatism-free Czerny-Turner imaging spectrometer using spherical mirrors,” Appl. Opt. 48(19), 3846–3853 (2009). [CrossRef] [PubMed]
  32. www.ondaxinc.com
  33. L. Carretero, M. Ulibarrena, P. Acebal, S. Blaya, R. Madrigal, and A. Fimia, “Multiplexed holographic gratings for fabricating 3D photonic crystals in BB640 photographic emulsions,” Opt. Express 12(13), 2903–2908 (2004). [CrossRef] [PubMed]
  34. S. Massenot, J.-L. Kaiser, M. C. Perez, R. Chevallier, and J. L. de Bougrenet de la Tocnaye, “Multiplexed holographic transmission gratings recorded in holographic polymer-dispersed liquid crystals: static and dynamic studies,” Appl. Opt. 44(25), 5273–5280 (2005). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited