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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 1 — Jan. 3, 2011

Synchronized time-lens source for coherent Raman scattering microscopy

Ke Wang, Christian W. Freudiger, Jennifer H. Lee, Brian G. Saar, X. Sunney Xie, and Chris Xu  »View Author Affiliations


Optics Express, Vol. 18, Issue 23, pp. 24019-24024 (2010)
http://dx.doi.org/10.1364/OE.18.024019


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Abstract

We use the time-lens concept to demonstrate a new scheme for synchronization of two pulsed light sources for biological imaging. An all fiber, 1064 nm time-lens source is synchronized to a picosecond solid-state Ti: Sapphire mode-locked laser by using the mode-locked laser pulses as the clock. We demonstrate the application of this synchronized source for CARS and SRS imaging by imaging mouse tissues. Synchronized two wavelength pulsed source is an important technical difficulty for CARS and SRS imaging. The time-lens source demonstrated here may provide an all fiber, user friendly alternative for future SRS imaging.

© 2010 OSA

OCIS Codes
(060.2380) Fiber optics and optical communications : Fiber optics sources and detectors
(320.7090) Ultrafast optics : Ultrafast lasers
(180.5655) Microscopy : Raman microscopy

ToC Category:
Microscopy

History
Original Manuscript: October 13, 2010
Revised Manuscript: October 27, 2010
Manuscript Accepted: October 28, 2010
Published: November 2, 2010

Virtual Issues
Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Ke Wang, Christian W. Freudiger, Jennifer H. Lee, Brian G. Saar, X. Sunney Xie, and Chris Xu, "Synchronized time-lens source for coherent Raman scattering microscopy," Opt. Express 18, 24019-24024 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-23-24019


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