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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 7 — Apr. 26, 2010

2D and 3D X-ray phase retrieval of multi-material objects using a single defocus distance

M.A. Beltran, D.M. Paganin, K. Uesugi, and M.J. Kitchen  »View Author Affiliations


Optics Express, Vol. 18, Issue 7, pp. 6423-6436 (2010)
http://dx.doi.org/10.1364/OE.18.006423


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Abstract

A method of tomographic phase retrieval is developed for multi-material objects whose components each have a distinct complex refractive index. The phase-retrieval algorithm, based on the Transport-of-Intensity equation, utilizes propagation-based X-ray phase contrast images acquired at a single defocus distance for each tomographic projection. The method requires a priori knowledge of the complex refractive index for each material present in the sample, together with the total projected thickness of the object at each orientation. The requirement of only a single defocus distance per projection simplifies the experimental setup and imposes no additional dose compared to conventional tomography. The algorithm was implemented using phase contrast data acquired at the SPring-8 Synchrotron facility in Japan. The three-dimensional (3D) complex refractive index distribution of a multi-material test object was quantitatively reconstructed using a single X-ray phase-contrast image per projection. The technique is robust in the presence of noise, compared to conventional absorption based tomography.

© 2010 OSA

OCIS Codes
(100.5070) Image processing : Phase retrieval
(100.6950) Image processing : Tomographic image processing
(340.7440) X-ray optics : X-ray imaging
(090.1995) Holography : Digital holography

ToC Category:
Image Processing

History
Original Manuscript: November 30, 2009
Revised Manuscript: January 14, 2010
Manuscript Accepted: February 5, 2010
Published: March 15, 2010

Virtual Issues
Vol. 5, Iss. 7 Virtual Journal for Biomedical Optics

Citation
M.A. Beltran, D.M. Paganin, K. Uesugi, and M.J. Kitchen, "2D and 3D X-ray phase retrieval of
multi-material objects using a
single defocus distance," Opt. Express 18, 6423-6436 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-7-6423


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