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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 9 — Jul. 6, 2010

Generic real-time uniform K-space sampling method for high-speed swept-Source optical coherence tomography

Jiefeng Xi, Li Huo, Jiasong Li, and Xingde Li  »View Author Affiliations


Optics Express, Vol. 18, Issue 9, pp. 9511-9517 (2010)
http://dx.doi.org/10.1364/OE.18.009511


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Abstract

We developed a universal, real-time uniform K-space sampling (Rt-UKSS) method for high-speed swept-source optical coherence tomography (SS-OCT). An external clock uniform in K-space was generated. The clock was synchronized with the zero-crossing time of an interferometric calibration signal and used as triggers for a high-speed data acquisition system in a point-by-point fashion, hence enabling uniform data sampling in K-space. Different from the numerical calibration algorithm commonly used in an SS-OCT system, the method reported here does not require over-sampling, thus greatly reducing the demand for digitization, data processing and storage speed. The Rt-UKSS method is adaptive and applicable to a generic SS-OCT system of a wide range of A-scan rates without special adjustment. We successfully implemented the Rt-UKSS method in an SS-OCT system based on a Fourier-domain mode-locked laser (FDML) of a 40-kHz scanning rate. Real-time imaging of biological tissues using such a system was demonstrated with a measured axial resolution of 9.3 μm and detection sensitivity greater than 120dB.

© 2010 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Imaging Systems

History
Original Manuscript: March 17, 2010
Revised Manuscript: April 6, 2010
Manuscript Accepted: April 18, 2010
Published: April 21, 2010

Virtual Issues
Vol. 5, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Jiefeng Xi, Li Huo, Jiasong Li, and Xingde Li, "Generic real-time uniform K-space sampling method for high-speed swept-Source optical coherence tomography," Opt. Express 18, 9511-9517 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-9-9511


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References

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