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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 8 — Aug. 26, 2011

Modeling optical properties of human skin using Mie theory for particles with different size distributions and refractive indices

A. Bhandari, B. Hamre, Ø. Frette, K. Stamnes, and J. J. Stamnes  »View Author Affiliations


Optics Express, Vol. 19, Issue 15, pp. 14549-14567 (2011)
http://dx.doi.org/10.1364/OE.19.014549


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Abstract

We used size distributions of volume equivalent spherical particles with complex refractive index to model the inherent optical properties (IOPs) in four different layers of human skin at ten different wavelengths in the visible and near-infrared spectral bands. For each layer, we first computed the size-averaged absorption coefficient, scattering coefficient, and asymmetry factor for the collection of particles in a host medium using Mie theory and compared these IOPs in each layer with those obtained from a bio-optical model (BOM). This procedure was repeated, using an optimization scheme, until satisfactory agreement was obtained between the IOPs obtained from the particle size distribution and those given by the BOM. The size distribution as well as the complex refractive index of the particles, obtained from this modeling exercise, can be used to compute the phase matrix, which is an essential input to model polarized light transport in human skin tissue.

© 2011 OSA

OCIS Codes
(000.1430) General : Biology and medicine
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(290.5850) Scattering : Scattering, particles

ToC Category:
Scattering

History
Original Manuscript: April 28, 2011
Revised Manuscript: June 22, 2011
Manuscript Accepted: June 23, 2011
Published: July 14, 2011

Virtual Issues
Vol. 6, Iss. 8 Virtual Journal for Biomedical Optics

Citation
A. Bhandari, B. Hamre, Ø. Frette, K. Stamnes, and J. J. Stamnes, "Modeling optical properties of human skin using Mie theory for particles with different size distributions and refractive indices," Opt. Express 19, 14549-14567 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-15-14549


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