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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 9 — Oct. 3, 2011

Monte-Carlo-based phase retardation estimator for polarization sensitive optical coherence tomography

Lian Duan, Shuichi Makita, Masahiro Yamanari, Yiheng Lim, and Yoshiaki Yasuno  »View Author Affiliations

Optics Express, Vol. 19, Issue 17, pp. 16330-16345 (2011)

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A Monte-Carlo-based phase retardation estimator is developed to correct the systematic error in phase retardation measurement by polarization sensitive optical coherence tomography (PS-OCT). Recent research has revealed that the phase retardation measured by PS-OCT has a distribution that is neither symmetric nor centered at the true value. Hence, a standard mean estimator gives us erroneous estimations of phase retardation, and it degrades the performance of PS-OCT for quantitative assessment. In this paper, the noise property in phase retardation is investigated in detail by Monte-Carlo simulation and experiments. A distribution transform function is designed to eliminate the systematic error by using the result of the Monte-Carlo simulation. This distribution transformation is followed by a mean estimator. This process provides a significantly better estimation of phase retardation than a standard mean estimator. This method is validated both by numerical simulations and experiments. The application of this method to in vitro and in vivo biological samples is also demonstrated.

© 2011 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.2130) Instrumentation, measurement, and metrology : Ellipsometry and polarimetry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(110.5405) Imaging systems : Polarimetric imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 5, 2011
Revised Manuscript: July 22, 2011
Manuscript Accepted: August 3, 2011
Published: August 10, 2011

Virtual Issues
Vol. 6, Iss. 9 Virtual Journal for Biomedical Optics

Lian Duan, Shuichi Makita, Masahiro Yamanari, Yiheng Lim, and Yoshiaki Yasuno, "Monte-Carlo-based phase retardation estimator for polarization sensitive optical coherence tomography," Opt. Express 19, 16330-16345 (2011)

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