OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 9 — Oct. 3, 2011

Polarimetry noise in fiber-based optical coherence tomography instrumentation

Ellen Ziyi Zhang and Benjamin J. Vakoc  »View Author Affiliations


Optics Express, Vol. 19, Issue 18, pp. 16830-16842 (2011)
http://dx.doi.org/10.1364/OE.19.016830


View Full Text Article

Enhanced HTML    Acrobat PDF (2977 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

High noise levels in fiber-based polarization-sensitive optical coherence tomography (PS-OCT) have broadly limited its clinical utility. In this study we investigate contribution of polarization mode dispersion (PMD) to the polarimetry noise. We develop numerical models of the PS-OCT system including PMD and validate these models with empirical data. Using these models, we provide a framework for predicting noise levels, for processing signals to reduce noise, and for designing an optimized system.

© 2011 OSA

OCIS Codes
(120.5410) Instrumentation, measurement, and metrology : Polarimetry
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(260.1440) Physical optics : Birefringence
(260.5430) Physical optics : Polarization

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 1, 2011
Revised Manuscript: July 1, 2011
Manuscript Accepted: July 11, 2011
Published: August 15, 2011

Virtual Issues
Vol. 6, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Ellen Ziyi Zhang and Benjamin J. Vakoc, "Polarimetry noise in fiber-based optical coherence tomography instrumentation," Opt. Express 19, 16830-16842 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-18-16830


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181 (1991). [CrossRef] [PubMed]
  2. M. R. Hee, D. Huang, E. A. Swanson, and J. G. Fujimoto, “Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging,” J. Opt. Soc. Am. B 9, 903–908 (1992). [CrossRef]
  3. J. F. de Boer, T. E. Milner, M. J. C. van Gemert, and J. S. Nelson, “Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography,” Opt. Lett. 22, 934–936 (1997). [CrossRef] [PubMed]
  4. E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of bire-fringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9, 94–102 (2004). [CrossRef] [PubMed]
  5. M. Zhao and J. A. Izatt, “Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging,” Opt. Lett. 34, 205–207 (2009). [CrossRef] [PubMed]
  6. E. Götzinger, M. Pircher, B. Baumann, C. Ahlers, W. Geitzenauer, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Three-dimensional polarization sensitive OCT imaging and interactive display of the human retina,” Opt. Express 17, 4151–4165 (2009). http://www.opticsinfobase.org/abstract.cfm?URI=oe-17-5-4151 [CrossRef] [PubMed]
  7. A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, “Tissue discrimination in anterior eye using three optical parameters obtained by polarization sensitive optical coherence tomography,” Opt. Express 17, 17426–17440 (2009). http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-20-17426 [CrossRef] [PubMed]
  8. C. E. Saxer, J. F. de Boer, B. H. Park, Y. Zhao, Z. Chen, and J. S. Nelson, “High-speed fiber-based polarization-sensitive optical coherence tomography of in vivo human skin,” Opt. Lett. 25, 1355–1357 (2000). [CrossRef]
  9. B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6, 474–479 (2001). [CrossRef] [PubMed]
  10. M. Todorovic, S. Jiao, J. Ai, D. Pereda-Cubin, G. Stoica, and L. V. Wang, “In vivo burn imaging using Mueller optical coherence tomography,” Opt. Express 16, 10279–10284 (2008). http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-14-10279 [CrossRef] [PubMed]
  11. S. D. Giattina, B. K. Courtney, P. R. Herz, M. Harman, S. Shortkroff, D. L. Stamper, B. Liu, d., J. G. Fujimoto, and M. E. Brezinski, “Assessment of coronary plaque collagen with polarization sensitive optical coherence tomography (PS-OCT),” Int. J. Cardiol. 107, 400–409 (2006). [CrossRef] [PubMed]
  12. S. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, E. F. Halpern, S. L. Houser, B. E. Bouma, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49, 1474–1481 (2007). [CrossRef] [PubMed]
  13. J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7, 359–371 (2002). [CrossRef] [PubMed]
  14. K. Schoenenberger, B. W. Colston, D. J. Maitland, L. B. Da Silva, and M. J. Everett, “Mapping of Birefringence and Thermal Damage in Tissue by use of Polarization-Sensitive Optical Coherence Tomography,” Appl. Opt. 37, 6026–6036 (1998). [CrossRef]
  15. S. Makita, M. Yamanari, and Y. Yasuno, “Generalized Jones matrix optical coherence tomography: performance and local birefringence imaging,” Opt. Express 18, 854–876 (2010). http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-2-854 [CrossRef] [PubMed]
  16. B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography,” Opt. Lett. 30, 2587–2589 (2005). [CrossRef] [PubMed]
  17. S. Yun, G. Tearney, J. de Boer, and B. Bouma, “Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting,” Opt. Express 12, 4822–4828 (2004). http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-12-20-4822 [CrossRef] [PubMed]
  18. P. Leong and S. Carlile, “Methods for spherical data analysis and visualization,” J. Neurosci. Methods 80, 191–200 (1998). [CrossRef] [PubMed]
  19. E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16, 16410–16422 (2008). http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-21-16410 [CrossRef] [PubMed]
  20. N. Vansteenkiste, P. Vignolo, and A. Aspect, “Optical reversibility theorems for polarization: Application to remote control of polarization,” J. Opt. Soc. Am. A 10, 2240–2245 (1993). [CrossRef]
  21. N. Gisin and B. Huttner, “Combined effects of polarization mode dispersion and polarization dependent loss in optical fibers,” Opt. Commun. , 142, 119–125 (1997). [CrossRef]
  22. P. Lu, L. Chen, and X. Bao, “Polarization mode dispersion and polarization dependent loss for a pulse in single-mode fibers,” J. Lightwave Technol. , 19, 856–860 (2001). [CrossRef]
  23. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, “Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging,” Nat. Med. 15, 1219–1223 (2009). [CrossRef] [PubMed]
  24. D. Waddy, L. Chen, and X. Bao, “A dynamical polarization mode dispersion emulator,” J. Lightwave Technol. , 4,534–536 (2003).
  25. C. D. Poole and D. L. Favin, “Polarization-mode dispersion measurements based on transmission spectra through a polarizer,” J. Lightwave Technol. , 12, 917–929 (1994). [CrossRef]
  26. E. Götzinger, M. Pircher, B. Baumann, C. Hirn, C. Vass, and C. K. Hitzenberger, “Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison,” J. Biophoton. 1, 129–139 (2008). [CrossRef]
  27. N. I. Fisher, T. Lewis, and B. J. J. Embleton, Statistical Analysis of Spherical Data (Cambridge U. Press, 1993).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited