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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 2 — Feb. 1, 2012

Enhanced resolution of microscopic objects by image inversion interferometry

D. Weigel, R. Foerster, H. Babovsky, A. Kiessling, and R. Kowarschik  »View Author Affiliations


Optics Express, Vol. 19, Issue 27, pp. 26451-26462 (2011)
http://dx.doi.org/10.1364/OE.19.026451


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Abstract

We demonstrate in experiment that the resolution of a conventional light microscope can be enhanced by 26% with the help of an image inverting interferometer. In order to prove this statement, we measured the point spread function of the system as well as the resolution of two-point objects. Additionally, the contrast transmission function of the interferometric setup was measured and compared to the results gained with a conventional wide-field microscope. Using the interferometric system, the spatial frequencies near the cutoff-frequency were far better transmitted than by the conventional microscope. Finally, we demonstrate the improved resolution with the help of images of two-dimensional structures.

© 2011 OSA

OCIS Codes
(110.0180) Imaging systems : Microscopy
(110.2970) Imaging systems : Image detection systems
(180.3170) Microscopy : Interference microscopy
(180.5810) Microscopy : Scanning microscopy
(350.5730) Other areas of optics : Resolution

ToC Category:
Microscopy

History
Original Manuscript: September 13, 2011
Revised Manuscript: November 18, 2011
Manuscript Accepted: November 20, 2011
Published: December 12, 2011

Virtual Issues
Vol. 7, Iss. 2 Virtual Journal for Biomedical Optics

Citation
D. Weigel, R. Foerster, H. Babovsky, A. Kiessling, and R. Kowarschik, "Enhanced resolution of microscopic objects by image inversion interferometry," Opt. Express 19, 26451-26462 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-27-26451


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