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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

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  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 3 — Mar. 18, 2011

Real-time bulk-motion-correction free Doppler variance optical coherence tomography for choroidal capillary vasculature imaging

Gangjun Liu, Wenjuan Qi, Lingfeng Yu, and Zhongping Chen  »View Author Affiliations


Optics Express, Vol. 19, Issue 4, pp. 3657-3666 (2011)
http://dx.doi.org/10.1364/OE.19.003657


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Abstract

In this paper, we analyze the retinal and choroidal blood vasculature in the posterior segment of the human eye with optimized color Doppler and Doppler variance optical coherence tomography. Depth-resolved structure, color Doppler and Doppler variance images are compared. Blood vessels down to the capillary level were detected and visualized with the optimized optical coherence color Doppler and Doppler variance method. For in-vivo imaging of human eyes, bulk-motion induced bulk phase must be identified and removed before using the color Doppler method. It was found that the Doppler variance method is not sensitive to bulk-motion and the method can be used without correcting the bulk-motion when the sample-movement-induced velocity changes gradually. Real-time processing and displaying of the structure and blood vessel images are very interesting and is demonstrated using a dual quad-core Central Processing Unit (CPU) workstation. High resolution images of choroidal capillary of the vasculature network with phased-resolved color Doppler and Doppler variance are shown.

© 2011 OSA

OCIS Codes
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 24, 2010
Revised Manuscript: January 15, 2011
Manuscript Accepted: January 20, 2011
Published: February 10, 2011

Virtual Issues
Vol. 6, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Gangjun Liu, Wenjuan Qi, Lingfeng Yu, and Zhongping Chen, "Real-time bulk-motion-correction free Doppler variance optical coherence tomography for choroidal capillary vasculature imaging," Opt. Express 19, 3657-3666 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-4-3657


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