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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 3 — Mar. 18, 2011

White-light spectral interferometry for surface plasmon resonance sensing applications

Siu Pang Ng, Chi Man Lawrence Wu, Shu Yuen Wu, and Ho Pui Ho  »View Author Affiliations


Optics Express, Vol. 19, Issue 5, pp. 4521-4527 (2011)
http://dx.doi.org/10.1364/OE.19.004521


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Abstract

A novel differential phase detecting surface plasmon resonance (SPR) sensor based on white-light spectral interferometry is presented. Our proposed scheme employs a white-light source for SPR excitation and measures the corresponding SPR phase change at the optimized coupling wavelength with fixed angle of incidence across the visible spectrum. Compared to existing laser based phase detecting schemes, this system offers optimal sensitivity and extended dynamic range of measurement without any compromise in phase detection resolution. Results obtained from sodium chloride solutions indicate that the detection limit is 2.6 × 10−7 RIU over a refractive index range of 10−2 RIU, which is considerably wider than that achievable by existing laser based approach, thus making our scheme very attractive for practical SPR sensing applications.

© 2011 OSA

OCIS Codes
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 12, 2011
Revised Manuscript: February 7, 2011
Manuscript Accepted: February 16, 2011
Published: February 23, 2011

Virtual Issues
Vol. 6, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Siu Pang Ng, Chi Man Lawrence Wu, Shu Yuen Wu, and Ho Pui Ho, "White-light spectral interferometry for surface plasmon resonance sensing applications," Opt. Express 19, 4521-4527 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-5-4521


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