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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 9 — Aug. 28, 2012

Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction

Xuan Liu, Yong Huang, and Jin U. Kang  »View Author Affiliations


Optics Express, Vol. 20, Issue 15, pp. 16567-16583 (2012)
http://dx.doi.org/10.1364/OE.20.016567


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Abstract

Hand-held OCT systems that offer physicians greater freedom to access imaging sites of interest could be useful for many clinical applications. In this study, by incorporating the theoretical speckle model into the decorrelation function, we have explicitly correlated the cross-correlation coefficient to the lateral displacement between adjacent A-scans. We used this model to develop and study a freehand-scanning OCT system capable of real-time scanning speed correction and distortion-free imaging—for the first time to the best our knowledge. To validate our model and the system, we performed a series of calibration experiments. Experimental results show that our method can extract lateral scanning distance. In addition, using the manually scanned hand-held OCT system, we obtained OCT images from various samples by freehand manual scanning, including images obtained from human in vivo.

© 2012 OSA

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(120.5800) Instrumentation, measurement, and metrology : Scanners
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(330.4150) Vision, color, and visual optics : Motion detection

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: May 24, 2012
Revised Manuscript: June 23, 2012
Manuscript Accepted: June 29, 2012
Published: July 6, 2012

Virtual Issues
Vol. 7, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Xuan Liu, Yong Huang, and Jin U. Kang, "Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction," Opt. Express 20, 16567-16583 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-15-16567


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References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991). [CrossRef] [PubMed]
  2. A. M. Zysk, F. T. Nguyen, A. L. Oldenburg, D. L. Marks, and S. A. Boppart, “Optical coherence tomography: a review of clinical development from bench to bedside,” J. Biomed. Opt.12(5), 051403–051421 (2007). [CrossRef] [PubMed]
  3. S. A. Boppart, B. E. Bouma, C. Pitris, G. J. Tearney, J. G. Fujimoto, and M. E. Brezinski, “Forward-imaging instruments for optical coherence tomography,” Opt. Lett.22(21), 1618–1620 (1997). [CrossRef] [PubMed]
  4. X. Li, C. Chudoba, T. Ko, C. Pitris, and J. G. Fujimoto, “Imaging needle for optical coherence tomography,” Opt. Lett.25(20), 1520–1522 (2000). [CrossRef] [PubMed]
  5. J. Wu, M. Conry, C. Gu, F. Wang, Z. Yaqoob, and C. Yang, “Paired-angle-rotation scanning optical coherence tomography forward-imaging probe,” Opt. Lett.31(9), 1265–1267 (2006). [CrossRef] [PubMed]
  6. S. Han, M. V. Sarunic, J. Wu, M. Humayun, and C. Yang, “Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection,” J. Biomed. Opt.13(2), 020505 (2008). [CrossRef] [PubMed]
  7. J. Han, M. Balicki, K. Zhang, X. Liu, J. Handa, R. Taylor, and J. U. Kang, “Common-path Fourier-domain optical coherence tomography with a fiber optic probe integrated Into a surgical needle,” Proceedings of CLEO Conference (2009).
  8. M. Balicki, J. Han, I. Iordachita, P. Gehlbach, J. Handa, J. U. Kang, and R. Taylor, “Single fiber optical coherence tomography microsurgical instruments for computer and robot-assisted retinal surgery,” Proceedings of the MICCAI Conference, London, 108–115 (2009).
  9. J. Ren, J. Wu, E. J. McDowell, and C. Yang, “Manual-scanning optical coherence tomography probe based on position tracking,” Opt. Lett.34(21), 3400–3402 (2009). [CrossRef] [PubMed]
  10. L. Huo, J. Xi, Y. Wu, and X. Li, “Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed for 3D OCT imaging,” Opt. Express18(14), 14375–14384 (2010). [CrossRef] [PubMed]
  11. W. G. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. P. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron.11(4), 806–810 (2005). [CrossRef]
  12. J.-F. Chen, J. B. Fowlkes, P. L. Carson, and J. M. Rubin, “Determination of scan-plane motion using speckle decorrelation: theoretical considerations and initial test,” Int. J. Imaging Syst. Technol.8(1), 38–44 (1997). [CrossRef]
  13. P. C. Li, C. J. Cheng, and C. K. Yeh, “On velocity estimation using speckle decorrelation,” IEEE Trans. Ultrason. Ferroelectr. Freq. Control48(4), 1084–1091 (2001). [CrossRef] [PubMed]
  14. A. Ahmad, S. G. Adie, E. J. Chaney, U. Sharma, and S. A. Boppart, “Cross-correlation-based image acquisition technique for manually-scanned optical coherence tomography,” Opt. Express17(10), 8125–8136 (2009). [CrossRef] [PubMed]
  15. K. Zhang, W. Wang, J. Han, and J. U. Kang, “A surface topology and motion compensation system for microsurgery guidance and intervention based on common-path optical coherence tomography,” IEEE Trans. Biomed. Eng.56(9), 2318–2321 (2009). [CrossRef] [PubMed]
  16. J. K. Barton and S. Stromski, “Flow measurement without phase information in optical coherence tomography images,” Opt. Express13(14), 5234–5239 (2005). [CrossRef] [PubMed]
  17. B. Lau, R. A. McLaughlin, A. Curatolo, R. W. Kirk, D. K. Gerstmann, and D. D. Sampson, “Imaging true 3D endoscopic anatomy by incorporating magnetic tracking with optical coherence tomography: proof-of-principle for airways,” Opt. Express18(26), 27173–27180 (2010). [CrossRef] [PubMed]
  18. J. M. Schmitt, S. H. Xiang, and K. M. Yung, “Speckle in optical coherence tomography,” J. Biomed. Opt.4(1), 95–105 (1999). [CrossRef]
  19. J. W. Goodman, Statistical Optics (Wiley, 1985).
  20. R. F. Wagner, M. F. Insana, and D. G. Brown, “Statistical properties of radio-frequency and envelope-detected signals with applications to medical ultrasound,” J. Opt. Soc. Am. A4(5), 910–922 (1987). [CrossRef] [PubMed]
  21. A. Yariv, Optical Electronics in Modern Communications (Oxford U. Press, 1991).
  22. Y. Liu, Y. Liang, G. Mu, and X. Zhu, “Deconvolution methods for image deblurring in optical coherence tomography,” J. Opt. Soc. Am. A26(1), 72–77 (2009). [CrossRef] [PubMed]
  23. P. D. Woolliams, R. A. Ferguson, C. Hart, A. Grimwood, and P. H. Tomlins, “Spatially deconvolved optical coherence tomography,” Appl. Opt.49(11), 2014–2021 (2010). [CrossRef] [PubMed]
  24. K. Zhang and J. U. Kang, “Graphics processing unit accelerated non-uniform fast Fourier transform for ultrahigh-speed, real-time Fourier-domain OCT,” Opt. Express18(22), 23472–23487 (2010). [CrossRef] [PubMed]
  25. X. Li, J. H. Han, X. Liu, and J. U. Kang, “Signal-to-noise ratio analysis of all-fiber common-path optical coherence tomography,” Appl. Opt.47(27), 4833–4840 (2008). [CrossRef] [PubMed]
  26. X. Liu and J. U. Kang, “Progress toward inexpensive endoscopic high-resolution common-path OCT,” Proc. SPIE7559, 755902, 755902-11 (2010). [CrossRef]
  27. J. U. Kang, J. Han, X. Liu, K. Zhang, C. Song, and P. Gehlbach, “Endoscopic functional Fourier domain common path optical coherence tomography for microsurgery,” IEEE J. Sel. Top. Quantum Electron.16(4), 781–792 (2010). [CrossRef]
  28. S. Sinch and C. Riviere, “Physiological tremor amplitude during retinal microsurgery,” Proc. 28th IEEE Northeast Bioeng. Conf, 171–172 (2002).
  29. J. Lee, V. Srinivasan, H. Radhakrishnan, and D. A. Boas, “Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex,” Opt. Express19(22), 21258–21270 (2011). [CrossRef] [PubMed]

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