OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 9 — Aug. 28, 2012

Real-time monitoring of the solution concentration variation during the crystallization process of protein-lysozyme by using digital holographic interferometry

Yanyan Zhang, Jianlin Zhao, Jianglei Di, Hongzhen Jiang, Qian Wang, Jun Wang, Yunzhu Guo, and Dachuan Yin  »View Author Affiliations


Optics Express, Vol. 20, Issue 16, pp. 18415-18421 (2012)
http://dx.doi.org/10.1364/OE.20.018415


View Full Text Article

Enhanced HTML    Acrobat PDF (1410 KB) Open Access





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We report a real-time measurement method of the solution concentration variation during the growth of protein-lysozyme crystals based on digital holographic interferometry. A series of holograms containing the information of the solution concentration variation in the whole crystallization process is recorded by CCD. Based on the principle of double-exposure holographic interferometry and the relationship between the phase difference of the reconstructed object wave and the solution concentration, the solution concentration variation with time for arbitrary point in the solution can be obtained, and then the two-dimensional concentration distribution of the solution during crystallization process can also be figured out under the precondition which the refractive index is constant through the light propagation direction. The experimental results turns out that it is feasible to in situ, full-field and real-time monitor the crystal growth process by using this method.

© 2012 OSA

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(260.1180) Physical optics : Crystal optics
(090.1995) Holography : Digital holography
(090.5694) Holography : Real-time holography

ToC Category:
Instrumentation, Measurement, and Metrology

History
Original Manuscript: June 7, 2012
Revised Manuscript: July 15, 2012
Manuscript Accepted: July 16, 2012
Published: July 26, 2012

Virtual Issues
Vol. 7, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Yanyan Zhang, Jianlin Zhao, Jianglei Di, Hongzhen Jiang, Qian Wang, Jun Wang, Yunzhu Guo, and Dachuan Yin, "Real-time monitoring of the solution concentration variation during the crystallization process of protein-lysozyme by using digital holographic interferometry," Opt. Express 20, 18415-18421 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-16-18415


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. S. Verma and P. J. Shlichta, “Imaging techniques for mapping solution parameters, growth rate, and surface features during the growth of crystals from solution,” Prog. Cryst. Growth Charact. Mater.54(1-2), 1–120 (2008). [CrossRef]
  2. F. Dubois, L. Joannes, O. Dupont, J. L. Dewandel, and J. C. Legros, “An integrated optical set-up for fluid-physics experiments under microgravity conditions,” Meas. Sci. Technol.10(10), 934–945 (1999). [CrossRef]
  3. S. Verma, “In situ and real-time monitoring of process parameters during growth of KDP crystal, an important ferroic material,” Phase Transit.83(9), 714–727 (2010). [CrossRef]
  4. F. Bedarida, “Developments of holographic interferometry applied to crystal growth from solution,” J. Cryst. Growth79(1-3), 43–49 (1986). [CrossRef]
  5. E. Plano, G. A. Dall’aglio, R. Chittofrati, S. Crivello, and F. Puppo, “A non-destructive interferometric technique for analysis of crystal growth and fluid dynamics,” Ann. Chim. Sci. Mat.26(1), 23–28 (2001). [CrossRef]
  6. E. H. Snell, J. R. Helliwell, T. J. Boggon, P. Lautenschlager, and L. Potthast, “Lysozyme crystal growth kinetics monitored using a Mach-Zehnder interferometer,” Acta Crystallogr. D Biol. Crystallogr.52(3), 529–533 (1996). [CrossRef] [PubMed]
  7. D. C. Yin, Y. Inatomi, H. M. Luo, H. S. Li, H. M. Lu, Y. J. Ye, and N. I. Wakayama, “Interferometry measurement of protein concentration evolution during crystallization and dissolution with improved reliability and versatility,” Meas. Sci. Technol.19(4), 045303 (2008). [CrossRef]
  8. A. Srivastava, K. Tsukamoto, E. Yokoyama, K. Murayama, and M. Fukuyama, “Fourier analysis based phase shift interferometric tomography for three-dimensional reconstruction of concentration field around a growing crystal,” J. Cryst. Growth312(15), 2254–2262 (2010). [CrossRef]
  9. J. Zhao, H. Miao, L. Duan, Q. Kang, and L. H. He, “The mass transfer process and the growth rate of NaCl crystal growth by evaporation based on temporal phase evaluation,” Opt. Lasers Eng.50(4), 540–546 (2012). [CrossRef]
  10. S. Maruyama, T. Shibata, and K. Tsukamoto, “Measurement of diffusion fields of solutions using real-time phase-shift interferometer and rapid heat-transfer control system,” Exp. Therm. Fluid Sci.19(1), 34–48 (1999). [CrossRef]
  11. S. Seebacher, W. Osten, T. Baumbach, and W. Jüptner, “The determination of material parameters of microcomponents using digital holography,” Opt. Lasers Eng.36(2), 103–126 (2001). [CrossRef]
  12. M. Grosse, J. Buehl, H. Babovsky, A. Kiessling, and R. Kowarschik, “3D shape measurement of macroscopic objects in digital off-axis holography using structured illumination,” Opt. Lett.35(8), 1233–1235 (2010). [CrossRef] [PubMed]
  13. B. Rappaz, P. Marquet, E. Cuche, Y. Emery, C. Depeursinge, and P. J. Magistretti, “Measurement of the integral refractive index and dynamic cell morphometry of living cells with digital holographic microscopy,” Opt. Express13(23), 9361–9373 (2005). [CrossRef] [PubMed]
  14. G. Rajshekhar, S. S. Gorthi, and P. Rastogi, “Estimation of multiple phases from a single fringe pattern in digital holographic interferometry,” Opt. Express20(2), 1281–1291 (2012). [CrossRef] [PubMed]
  15. W. Sun, J. Zhao, J. Di, Q. Wang, and L. Wang, “Real-time visualization of Karman vortex street in water flow field by using digital holography,” Opt. Express17(22), 20342–20348 (2009). [CrossRef] [PubMed]
  16. M. F. Toy, S. Richard, J. Kühn, A. Franco-Obregón, M. Egli, and C. Depeursinge, “Enhanced robustness digital holographic microscopy for demanding environment of space biology,” Biomed. Opt. Express3(2), 313–326 (2012). [CrossRef] [PubMed]
  17. M. M. Hossain and C. Shakher, “Temperature measurement in laminar free convective flow using digital holography,” Appl. Opt.48(10), 1869–1877 (2009). [CrossRef] [PubMed]
  18. S. Grilli, P. Ferraro, M. Paturzo, D. Alfieri, P. De Natale, M. de Angelis, S. De Nicola, A. Finizio, and G. Pierattini, “In-situ visualization, monitoring and analysis of electric field domain reversal process in ferroelectric crystals by digital holography,” Opt. Express12(9), 1832–1842 (2004). [CrossRef] [PubMed]
  19. J. Wang, J. L. Zhao, C. Qin, J. L. Di, A. Rauf, and H. Z. Jiang, “Digital holographic interferometry based on wavelength and angular multiplexing for measuring the ternary diffusion,” Opt. Lett.37(7), 1211–1213 (2012). [CrossRef] [PubMed]
  20. F. Charrière, B. Rappaz, J. Kühn, T. Colomb, P. Marquet, and C. Depeursinge, “Influence of shot noise on phase measurement accuracy in digital holographic microscopy,” Opt. Express15(14), 8818–8831 (2007). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4
 

Multimedia

Multimedia FilesRecommended Software
» Media 1: AVI (4035 KB)      QuickTime

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited