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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 10 — Oct. 5, 2012

Optics InfoBase > Virtual Journal for Biomedical Optics > Volume 7 > Issue 10 > Page 19148

Spectral-domain OCT with dual illumination and interlaced detection for simultaneous anterior segment and retina imaging

Hyun-Woo Jeong, Sang-Won Lee, and Beop-Min Kim  »View Author Affiliations


Optics Express, Vol. 20, Issue 17, pp. 19148-19159 (2012)
http://dx.doi.org/10.1364/OE.20.019148


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Abstract

We present Fourier-domain/spectral-domain optical coherence tomography (FD/SD-OCT) using a single spectrometer with dual illumination and interlaced detection at 830 nm, which can provide anterior segment and retinal tomograms simultaneously. Two orthogonal polarization components were used so that both parallel and focused beams could simultaneously be made incident on the eye. This configuration with a polarization-separated sample arm enables us to acquire images from the anterior segment and retina effectively with minimum loss of sample information. In the detector arm, a single spectrometer is illuminated via an ultrafast optical switch for interlaced detection. A graphical user interface (GUI) was built to control the optical switch for imaging the anterior segment and retina either simultaneously or individually. In addition, we implemented an off-pivot complex conjugate removal technique to double the imaging depth for anterior segment imaging. The axial resolution of our FD/SD-OCT system was measured to be ~6.7 μm in air, which corresponds to 4.9 μm in tissue (n = 1.35). The sensitivity was approximately 90 dB for both anterior segment and retina imaging when the acquisition speed was 35,000 A-scans per second and the depth position was near 120 μm from the zero-depth location. Finally, we demonstrated the feasibility of our system for simultaneous in vivo imaging of both the anterior segment and retina of a healthy human volunteer.

© 2012 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: May 11, 2012
Revised Manuscript: June 22, 2012
Manuscript Accepted: June 22, 2012
Published: August 6, 2012

Virtual Issues
Vol. 7, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Hyun-Woo Jeong, Sang-Won Lee, and Beop-Min Kim, "Spectral-domain OCT with dual illumination and interlaced detection for simultaneous anterior segment and retina imaging," Opt. Express 20, 19148-19159 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-17-19148


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