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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 11 — Oct. 31, 2012

Aluminum oxide nanostructure-based substrates for fluorescence enhancement

Xiang Li, Yuan He, Tianhua Zhang, and Long Que  »View Author Affiliations


Optics Express, Vol. 20, Issue 19, pp. 21272-21277 (2012)
http://dx.doi.org/10.1364/OE.20.021272


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Abstract

A new fluorescence enhancement technical platform based on anodic aluminum oxide (AAO) nanostructure substrate is reported for the first time. Several fluorophores have been examined on the AAO nanostructure substrates. Systematic experiments found that the enhancement factor can be up to two orders of magnitude compared to the fluorescence signals on a glass substrate, indicating its great potential for ultrasensitive fluorescence detection. Given the simple and cost-effective fabrication process of lithographically patterned AAO nanostructure, this type of AAO nanostructure platform has great potential applications, especially its integration with microdevices and microfluidic devices for fluorescence-based biological analysis.

© 2012 OSA

OCIS Codes
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
(180.2520) Microscopy : Fluorescence microscopy
(300.2530) Spectroscopy : Fluorescence, laser-induced

ToC Category:
Spectroscopy

History
Original Manuscript: June 4, 2012
Revised Manuscript: July 20, 2012
Manuscript Accepted: August 29, 2012
Published: September 4, 2012

Virtual Issues
Vol. 7, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Xiang Li, Yuan He, Tianhua Zhang, and Long Que, "Aluminum oxide nanostructure-based substrates for fluorescence enhancement," Opt. Express 20, 21272-21277 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-19-21272


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