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A reconstruction method for cone-beam differential x-ray phase-contrast computed tomographyJian Fu, Astrid Velroyen, Renbo Tan, Junwei Zhang, Liyuan Chen, Arne Tapfer, Martin Bech, and Franz Pfeiffer »View Author Affiliations
Jian Fu,1,*
Astrid Velroyen,2
Renbo Tan,1
Junwei Zhang,1
Liyuan Chen,1
Arne Tapfer,2
Martin Bech,2,3,4
and Franz Pfeiffer2
1Beijing University of Aeronautics and Astronautics, 100191 Beiijng, China 2Technische Universität München, 85748 Garching, Germany 3Lund University, 221 85 Lund, Sweden 4martin.bech@tum.de *Corresponding author: fujian706@buaa.edu.cn |
Optics Express, Vol. 20, Issue 19, pp. 21512-21519 (2012)
http://dx.doi.org/10.1364/OE.20.021512
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Abstract
Most existing differential phase-contrast computed tomography (DPC-CT) approaches are based on three kinds of scanning geometries, described by parallel-beam, fan-beam and cone-beam. Due to the potential of compact imaging systems with magnified spatial resolution, cone-beam DPC-CT has attracted significant interest. In this paper, we report a reconstruction method based on a back-projection filtration (BPF) algorithm for cone-beam DPC-CT. Due to the differential nature of phase contrast projections, the algorithm restrains from differentiation of the projection data prior to back-projection, unlike BPF algorithms commonly used for absorption-based CT data. This work comprises a numerical study of the algorithm and its experimental verification using a dataset measured with a three-grating interferometer and a micro-focus x-ray tube source. Moreover, the numerical simulation and experimental results demonstrate that the proposed method can deal with several classes of truncated cone-beam datasets. We believe that this feature is of particular interest for future medical cone-beam phase-contrast CT imaging applications.
© 2012 OSA
OCIS Codes
(110.7440) Imaging systems : X-ray imaging
(110.3175) Imaging systems : Interferometric imaging
(110.6955) Imaging systems : Tomographic imaging
ToC Category:
Imaging Systems
History
Original Manuscript: June 13, 2012
Manuscript Accepted: August 12, 2012
Published: September 5, 2012
Virtual Issues
Vol. 7, Iss. 11 Virtual Journal for Biomedical Optics
Citation
Jian Fu, Astrid Velroyen, Renbo Tan, Junwei Zhang, Liyuan Chen, Arne Tapfer, Martin Bech, and Franz Pfeiffer, "A reconstruction method for cone-beam differential x-ray phase-contrast computed tomography," Opt. Express 20, 21512-21519 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-19-21512
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References
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- G. H. Chen and Z. Qi, “Image reconstruction for fan-beam differential phase contrast computed tomography,” Phys. Med. Biol.53, 1015–1025 (2008). [CrossRef]
- S. Leng, T. G. Zhuang, B. E. Nett, and G. H. Chen, “Exact fan-beam image reconstruction algorithm for truncated projection data acquired from an asymmetric half-size detector,” Phys. Med. Biol.50, 1805–1820 (2005). [CrossRef]
- T. G. Zhuang, S. Leng, B. E. Nett, and G. H. Chen, “Fan-beam and cone-beam image reconstruction via filtering the backprojection image of differentiated projection data,” Phys. Med. Biol.49, 5489–5503 (2004). [CrossRef]
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- P. Cloetens, W. Ludwig, J. Baruchel, D. van Dyck, J. van Landuyt, J. P. Guigay, and M. Schlenker, “Holotomography:quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays,” Appl. Phys. Lett.75, 2912–2914 (1999). [CrossRef]
- M. Bech, T. H. Jensen, R. Feidenhans’l, O. Bunk, C. David, and F. Pfeiffer, “Soft-tissue phase-contrast tomography with an x-ray tube source,” Phys. Med. Biol.54, 2747–2753 (2009). [CrossRef]
- F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Brönnimann, C. Grünzweig, and C. David, “Hard-x-ray dark-field imaging using a grating interferometer,” Nature Mater.7, 134 (2008). [CrossRef]
- F. Pfeiffer, C. David, O. Bunk, T. Donath, M. Bech, G. Le Duc, A. Bravin, and P. Cloetens, “Region-of-interest tomography for grating-based differential phase-contrast imaging,” Phys. Rev.Lett.101, 168101 (2008). [CrossRef]
- F. Pfeiffer, C. Kottler, O. Bunk, and C. David, “Hard x-ray phase tomography with low-brilliance sources,” Phys. Rev. Lett.98, 108105 (2007). [CrossRef]
- F. Pfeiffer, T. Weitkamp, O. Bunk, and C. David, “Phase retrieval and differential phase-contrast imaging with low-brilliance x-ray sources,” Nat. Phys.2, 258–261 (2006). [CrossRef]
- T. Weitkamp, A. Diaz, C. David, F. Pfeiffer, M. Stampanoni, P. Cloetens, and E. Ziegler, “X-ray phase imaging with a grating interferometer,” Opt. Express13, 6296–6304 (2005). [CrossRef]
- F. A. Dilmanian, Z. Zhong, B. Ren, X. Y. Wu, L. D. Chapman, I. Orion, and W. C. Thomlinson, “Computed tomography of x-ray index of refraction using the diffraction enhanced imaging method,” Phys. Med.Biol.45, 933–946 (2000). [CrossRef]
- F. Pfeiffer, C. David, O. Bunk, T. Donath, M. Bech, G. Le Duc, A. Bravin, and P. Cloetens, “Region-of-interest tomography for grating-based differential phase-contrast imaging,” Phys. Rev.Lett.101, 168101 (2008). [CrossRef]
- F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Brönnimann, C. Grünzweig, and C. David, “Hard-x-ray dark-field imaging using a grating interferometer,” Nature Mater.7, 134 (2008). [CrossRef]
- M. Bech, T. H. Jensen, R. Feidenhans’l, O. Bunk, C. David, and F. Pfeiffer, “Soft-tissue phase-contrast tomography with an x-ray tube source,” Phys. Med. Biol.54, 2747–2753 (2009). [CrossRef]
- A. Bravin, J. Keyrilainen, M. Fernandez, S. Fiedler, C. Nemoz, M. L. Karjalainen-Lindsberg, M. Tenhunen, P. Virkkunen, M. Leidenius, K. V. Smitten, P. Sipila, and P. Suortti, “High-resolution ct by diffraction-enhanced x-ray imaging: mapping of breast tissue samples and comparison with their histo-pathology,” Phys. Med. Biol.52, 2197–2211 (2007). [CrossRef]
- A. Bravin, J. Keyrilainen, M. Fernandez, S. Fiedler, C. Nemoz, M. L. Karjalainen-Lindsberg, M. Tenhunen, P. Virkkunen, M. Leidenius, K. V. Smitten, P. Sipila, and P. Suortti, “High-resolution ct by diffraction-enhanced x-ray imaging: mapping of breast tissue samples and comparison with their histo-pathology,” Phys. Med. Biol.52, 2197–2211 (2007). [CrossRef]
- R. Fitzgerald, “Phase-sensitive x-ray imaging,” Phys. Today7, 23–26 (2000). [CrossRef]
- J. Fu, P. Li, Q. Wang, S. Wang, M. Bech, A. Tapfer, D. Hahn, and F. Pfeiffer, “A reconstruction method for equidistant fan-beam differential phase contrast computed tomography,” Phys. Med. Biol.56, 4259–4238 (2011). [CrossRef]
- A. Groso, M. Stampanoni, R. Abela, P. Schneider, S. Linga, and R. Müller, “Phase contrast tomography: an alternative approach,” Appl. Phys. Lett.88, 214104 (2006). [CrossRef]
- F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Brönnimann, C. Grünzweig, and C. David, “Hard-x-ray dark-field imaging using a grating interferometer,” Nature Mater.7, 134 (2008). [CrossRef]
- P. Cloetens, W. Ludwig, J. Baruchel, D. van Dyck, J. van Landuyt, J. P. Guigay, and M. Schlenker, “Holotomography:quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays,” Appl. Phys. Lett.75, 2912–2914 (1999). [CrossRef]
- J. Fu, P. Li, Q. Wang, S. Wang, M. Bech, A. Tapfer, D. Hahn, and F. Pfeiffer, “A reconstruction method for equidistant fan-beam differential phase contrast computed tomography,” Phys. Med. Biol.56, 4259–4238 (2011). [CrossRef]
- A. Momose, S. Kawamoto, I. Koyama, Y. Hamaishi, K. Takai, and Y. Suzuki, “Demonstration of x-ray talbot interferometry,” Jpn. J. Appl. Phys.42, L866–L868 (2003). [CrossRef]
- A. Momose, W. Yashiro, Y. Takeda, Y. Suzuki, and T. Hattori, “Phase tomography by x-ray talbot interferometry for biological imaging,” Jpn. J. Appl. Phys.45, 5254–5262 (2006). [CrossRef]
- F. Beckmann, K. Heise, B. Kolsch, U. Bonse, M. Rajewsky, and T. Biermann, “Three-dimensional imaging of nerve tissue by x-ray phase-contrast microtomography,” Biophys. J.76, 98–102 (1999). [CrossRef]
- P. J. McMahon, A. G. Peele, D. Paterson, J. J. A. Lin, T. H. K. Irving, I. McNulty, and K. A. Nugent, “Quantitative x-ray phase tomography with sub-micron resolution,” Opt. Commun.217, 53–58 (2003). [CrossRef]
- M. Bech, T. H. Jensen, R. Feidenhans’l, O. Bunk, C. David, and F. Pfeiffer, “Soft-tissue phase-contrast tomography with an x-ray tube source,” Phys. Med. Biol.54, 2747–2753 (2009). [CrossRef]
- I. Jerjen, V. Revol, C. Kottler, T. Luethi, U. Sennhauser, R. Kaufmann, and C. Urban, “Phase contrast cone beam tomography with an x-ray grating interferometer,” AIP Conf. Proc.1236, 227–231 (2010). [CrossRef]
- A. C. Kak and M. Slaney, Principles of Computerized Tomography (IEEE Press, 1987).
- A. Bravin, J. Keyrilainen, M. Fernandez, S. Fiedler, C. Nemoz, M. L. Karjalainen-Lindsberg, M. Tenhunen, P. Virkkunen, M. Leidenius, K. V. Smitten, P. Sipila, and P. Suortti, “High-resolution ct by diffraction-enhanced x-ray imaging: mapping of breast tissue samples and comparison with their histo-pathology,” Phys. Med. Biol.52, 2197–2211 (2007). [CrossRef]
- I. Jerjen, V. Revol, C. Kottler, T. Luethi, U. Sennhauser, R. Kaufmann, and C. Urban, “Phase contrast cone beam tomography with an x-ray grating interferometer,” AIP Conf. Proc.1236, 227–231 (2010). [CrossRef]
- A. Momose, S. Kawamoto, I. Koyama, Y. Hamaishi, K. Takai, and Y. Suzuki, “Demonstration of x-ray talbot interferometry,” Jpn. J. Appl. Phys.42, L866–L868 (2003). [CrossRef]
- A. Tapfer, M. Bech, B. Pauwels, X. Liu, P. Bruyndonckx, A. Sasov, J. Kenntner, J. Mohr, M. Walter, J. Schulz, and F. Pfeiffer, “Development of a prototype gantry system for preclinical x-ray phase-contrast computed tomography,” Med. Phys.38, 5910–5915 (2011). [CrossRef]
- A. Bravin, J. Keyrilainen, M. Fernandez, S. Fiedler, C. Nemoz, M. L. Karjalainen-Lindsberg, M. Tenhunen, P. Virkkunen, M. Leidenius, K. V. Smitten, P. Sipila, and P. Suortti, “High-resolution ct by diffraction-enhanced x-ray imaging: mapping of breast tissue samples and comparison with their histo-pathology,” Phys. Med. Biol.52, 2197–2211 (2007). [CrossRef]
- C. Raven, A. Snigirev, I. Snigireva, P. Spanne, A. Souvorov, and V. Kohn, “Phase-contrast microtomography with coherent high-energy synchrotron x rays,” Appl. Phys. Lett.69, 1826–1828 (1996). [CrossRef]
- F. Beckmann, K. Heise, B. Kolsch, U. Bonse, M. Rajewsky, and T. Biermann, “Three-dimensional imaging of nerve tissue by x-ray phase-contrast microtomography,” Biophys. J.76, 98–102 (1999). [CrossRef]
- I. Jerjen, V. Revol, C. Kottler, T. Luethi, U. Sennhauser, R. Kaufmann, and C. Urban, “Phase contrast cone beam tomography with an x-ray grating interferometer,” AIP Conf. Proc.1236, 227–231 (2010). [CrossRef]
- F. Pfeiffer, C. Kottler, O. Bunk, and C. David, “Hard x-ray phase tomography with low-brilliance sources,” Phys. Rev. Lett.98, 108105 (2007). [CrossRef]
- A. Momose, S. Kawamoto, I. Koyama, Y. Hamaishi, K. Takai, and Y. Suzuki, “Demonstration of x-ray talbot interferometry,” Jpn. J. Appl. Phys.42, L866–L868 (2003). [CrossRef]
- F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Brönnimann, C. Grünzweig, and C. David, “Hard-x-ray dark-field imaging using a grating interferometer,” Nature Mater.7, 134 (2008). [CrossRef]
- F. Pfeiffer, C. David, O. Bunk, T. Donath, M. Bech, G. Le Duc, A. Bravin, and P. Cloetens, “Region-of-interest tomography for grating-based differential phase-contrast imaging,” Phys. Rev.Lett.101, 168101 (2008). [CrossRef]
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