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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 3 — Feb. 29, 2012

Dual-beam-scan Doppler optical coherence angiography for birefringence-artifact-free vasculature imaging

Shuichi Makita, Franck Jaillon, Masahiro Yamanari, and Yoshiaki Yasuno  »View Author Affiliations


Optics Express, Vol. 20, Issue 3, pp. 2681-2692 (2012)
http://dx.doi.org/10.1364/OE.20.002681


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Abstract

Dual-beam-scan Doppler optical coherence angiography (DB-OCA) enables high-speed, high-sensitivity blood flow imaging. However, birefringence of biological tissues is an obstacle to vasculature imaging. Here, the influence of polarization and birefringence on DB-OCA imaging was analyzed. A DB-OCA system without birefringence artifact has been developed by introducing a Faraday rotator. The performance was confirmed in vitro using chicken muscle and in vivo using the human eye. Birefringence artifacts due to birefringent tissues were suppressed. Micro-vasculatures in the lamina cribrosa and nerve fiber layer of human eyes were visualized in vivo. High-speed and high-sensitivity micro-vasculature imaging involving birefringent tissues is available with polarization multiplexing DB-OCA.

© 2012 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.4470) Medical optics and biotechnology : Ophthalmology
(260.5430) Physical optics : Polarization

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 9, 2011
Revised Manuscript: January 5, 2012
Manuscript Accepted: January 9, 2012
Published: January 23, 2012

Virtual Issues
Vol. 7, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Shuichi Makita, Franck Jaillon, Masahiro Yamanari, and Yoshiaki Yasuno, "Dual-beam-scan Doppler optical coherence angiography for birefringence-artifact-free vasculature imaging," Opt. Express 20, 2681-2692 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-3-2681


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